[HTML][HTML] Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex

F Hagen, K Khayhan, B Theelen, A Kolecka… - Fungal genetics and …, 2015 - Elsevier
Phylogenetic analysis of 11 genetic loci and results from many genotyping studies revealed
significant genetic diversity with the pathogenic Cryptococcus gattii/Cryptococcus …

Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis

KJ Kwon-Chung, JA Fraser… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Cryptococcus neoformans and Cryptococcus gattii are the two etiologic agents of
cryptococcosis. They belong to the phylum Basidiomycota and can be readily distinguished …

Fungal brain infection modelled in a human-neurovascular-unit-on-a-chip with a functional blood–brain barrier

J Kim, KT Lee, JS Lee, J Shin, B Cui, K Yang… - Nature biomedical …, 2021 - nature.com
The neurovascular unit, which consists of vascular cells surrounded by astrocytic end-feet
and neurons, controls cerebral blood flow and the permeability of the blood–brain barrier …

Pulmonary cryptococcosis: a review of pathobiology and clinical aspects

F Setianingrum, R Rautemaa-Richardson… - Medical …, 2019 - academic.oup.com
Pulmonary cryptococcosis is an important opportunistic invasive mycosis in
immunocompromised patients, but it is also increasingly seen in immunocompetent patients …

Cryptococcus gattii infections

SCA Chen, W Meyer, TC Sorrell - Clinical microbiology reviews, 2014 - Am Soc Microbiol
Understanding of the taxonomy and phylogeny of Cryptococcus gattii has been advanced by
modern molecular techniques. C. gattii probably diverged from Cryptococcus neoformans …

The case for adopting the “species complex” nomenclature for the etiologic agents of cryptococcosis

KJ Kwon-Chung, JE Bennett, BL Wickes, W Meyer… - MSphere, 2017 - Am Soc Microbiol
Cryptococcosis is a potentially lethal disease of humans/animals caused by Cryptococcus
neoformans and Cryptococcus gattii. Distinction between the two species is based on …

Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM

CC Chang, TS Harrison, TA Bicanic… - The Lancet Infectious …, 2024 - thelancet.com
Cryptococcosis is a major worldwide disseminated invasive fungal infection. Cryptococcosis,
particularly in its most lethal manifestation of cryptococcal meningitis, accounts for …

[HTML][HTML] Cryptococcosis diagnosis and treatment: What do we know now

JR Perfect, T Bicanic - Fungal Genetics and Biology, 2015 - Elsevier
Cryptococcosis has evolved into a major invasive fungal disease over the last century. Its
primary epidemiology has been focused on three major outbreaks of disease that reflects …

[HTML][HTML] A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans

ST Denham, B Brammer, KY Chung, MA Wambaugh… - Cell host & …, 2022 - cell.com
Environmental pathogens move from ecological niches to mammalian hosts, requiring
adaptation to dramatically different environments. Microbes that disseminate farther …

Trojan horse transit contributes to blood-brain barrier crossing of a eukaryotic pathogen

FH Santiago-Tirado, MD Onken, JA Cooper, RS Klein… - MBio, 2017 - Am Soc Microbiol
The blood-brain barrier (BBB) protects the central nervous system (CNS) by restricting the
passage of molecules and microorganisms. Despite this barrier, however, the fungal …