Fungal pathogens cause more than a billion human infections every year, resulting in more
than 1.6 million deaths annually. Understanding the natural history and evolutionary ecology …

The opportunistic protist Acanthamoeba, which interacts with other microbes such as
bacteria, fungi, and viruses, shows significant similarity in cellular and functional aspects to …

One billion people worldwide are affected by fungal pathogens, of which 1.6 million
succumb to fungal infections per year. This review discusses the emergence and evolution …

The extracellular capsule is a major virulence factor, but its ubiquity in free-living bacteria
with large environmental breadths suggests that it shapes adaptation to novel niches. Yet …

In environments characterized by extended multi-stress conditions, pathogens develop a
variety of immune escape mechanisms to enhance their ability to infect the host. The …

Investigation of fungal biology has been frequently motivated by the fact that many fungal
species are important plant and animal pathogens. Such efforts have contributed …

Cryptococcus neoformans is the causative agent of cryptococcosis, a disease with poor
patient outcomes that accounts for approximately 180,000 deaths each year. Patient …

Melanin is a major virulence factor in pathogenic fungi that enhances the ability of fungal
cells to resist immune clearance. Cryptococcus neoformans is an important human …

Systemic cryptococcosis is fatal without treatment. Even with the current antifungal therapies,
this disease kills 180,000 of 225,000 infected people annually. Exposure to the causative …

A pet cockatoo was the suspected source of Cryptococcus neoformans recovered from an
immunocompromised patient with cryptococcosis based on molecular analyses available in …