The Intracellular Life of Cryptococcus neoformans

C Coelho, AL Bocca… - Annual Review of …, 2014 - annualreviews.org
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

Cryptococcus

SS Li, CH Mody - Proceedings of the American Thoracic Society, 2010 - atsjournals.org
Cryptococcus is a unique environmental fungus. Among the more than three dozen species
of Cryptococcus, only C. neoformans and C. gattii commonly cause disease. Although many …

Animal Models of Cryptococcus neoformans in Identifying Immune Parameters Associated With Primary Infection and Reactivation of Latent Infection

TG Normile, AM Bryan, M Del Poeta - Frontiers in Immunology, 2020 - frontiersin.org
Cryptococcus species are environmental fungal pathogens and the causative agents of
cryptococcosis. Infection occurs upon inhalation of infectious particles, which proliferate in …

Adaptive Immunity to Cryptococcus neoformans Infections

L Mukaremera, K Nielsen - Journal of fungi, 2017 - mdpi.com
The Cryptococcus neoformans/Cryptococcus gattii species complex is a group of fungal
pathogens with different phenotypic and genotypic diversity that cause disease in …

Interaction of the pathogenic mold Aspergillus fumigatus with lung epithelial cells

N Osherov - Frontiers in microbiology, 2012 - frontiersin.org
Aspergillus fumigatus is an opportunistic environmental mold that can cause severe allergic
responses in atopic individuals and poses a life-threatening risk for severely …

Protective interaction of human phagocytic APC subsets with Cryptococcus neoformans induces genes associated with metabolism and antigen presentation

BN Nelson, CS Daugherty, RR Sharp… - Frontiers in …, 2022 - frontiersin.org
Cryptococcal meningitis is the most common cause of meningitis among HIV/AIDS patients
in sub-Saharan Africa, and worldwide causes over 223,000 cases leading to more than …

Mechanisms of Pulmonary Escape and Dissemination by Cryptococcus neoformans

ST Denham, JCS Brown - Journal of Fungi, 2018 - mdpi.com
Cryptococcus neoformans is a common environmental saprophyte and human fungal
pathogen that primarily causes disease in immunocompromised individuals. Similar to many …

Molecular and cellular characteristics of ABCA3 mutations associated with diffuse parenchymal lung diseases in children

F Flamein, L Riffault, C Muselet-Charlier… - Human molecular …, 2012 - academic.oup.com
ABCA3 (ATP-binding cassette subfamily A, member 3) is expressed in the lamellar bodies of
alveolar type II cells and is crucial to pulmonary surfactant storage and homeostasis. ABCA3 …

Functional Analysis of Host Factors that Mediate the Intracellular Lifestyle of Cryptococcus neoformans

QM Qin, J Luo, X Lin, J Pei, L Li, TA Ficht… - PLoS …, 2011 - journals.plos.org
Cryptococcus neoformans (Cn), the major causative agent of human fungal
meningoencephalitis, replicates within phagolysosomes of infected host cells. Despite more …

Human airway epithelium responses to invasive fungal infections: A critical partner in innate immunity

AJ Crossen, RA Ward, JL Reedy, MV Surve, BS Klein… - Journal of Fungi, 2022 - mdpi.com
The lung epithelial lining serves as the primary barrier to inhaled environmental toxins,
allergens, and invading pathogens. Pulmonary fungal infections are devastating and carry …