[HTML][HTML] Intercellular mitochondrial transfer as a means of tissue revitalization

D Liu, Y Gao, J Liu, Y Huang, J Yin, Y Feng… - Signal transduction and …, 2021 - nature.com
As the crucial powerhouse for cell metabolism and tissue survival, the mitochondrion
frequently undergoes morphological or positional changes when responding to various …

[HTML][HTML] Mechanisms underlying the protective effects of mesenchymal stem cell-based therapy

XL Fan, Y Zhang, X Li, QL Fu - Cellular and molecular life sciences, 2020 - Springer
Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …

[HTML][HTML] Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases

Z Liu, Y Sun, Z Qi, L Cao, S Ding - Cell & bioscience, 2022 - Springer
Mitochondria play a pivotal role in energy generation and cellular physiological processes.
These organelles are highly dynamic, constantly changing their morphology, cellular …

The power and potential of mitochondria transfer

N Borcherding, JR Brestoff - Nature, 2023 - nature.com
Mitochondria are believed to have originated through an ancient endosymbiotic process in
which proteobacteria were captured and co-opted for energy production and cellular …

[HTML][HTML] Mesenchymal stem cell-based therapy for cardiovascular disease: progress and challenges

L Bagno, KE Hatzistergos, W Balkan, JM Hare - Molecular Therapy, 2018 - cell.com
Administration of mesenchymal stem cells (MSCs) to diseased hearts improves cardiac
function and reduces scar. These effects occur via stimulation of endogenous repair …

[HTML][HTML] Regenerative abilities of mesenchymal stem cells through mitochondrial transfer

S Paliwal, R Chaudhuri, A Agrawal… - Journal of biomedical …, 2018 - Springer
The past decade has witnessed an upsurge in studies demonstrating mitochondrial transfer
as one of the emerging mechanisms through which mesenchymal stem cells (MSCs) can …

[HTML][HTML] Mitochondrial-targeted therapy for doxorubicin-induced cardiotoxicity

BB Wu, KT Leung, ENY Poon - International journal of molecular sciences, 2022 - mdpi.com
Anthracyclines, such as doxorubicin, are effective chemotherapeutic agents for the treatment
of cancer, but their clinical use is associated with severe and potentially life-threatening …

[HTML][HTML] Bioenergetic crosstalk between mesenchymal stem cells and various ocular cells through the intercellular trafficking of mitochondria

D Jiang, FX Chen, H Zhou, YY Lu, H Tan, SJ Yu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Mitochondrial disorders preferentially affect tissues with high energy
requirements, such as the retina and corneal endothelium, in human eyes. Mesenchymal …

The mini player with diverse functions: extracellular vesicles in cell biology, disease, and therapeutics

A Thakur, X Ke, YW Chen, P Motallebnejad… - Protein & …, 2022 - academic.oup.com
Extracellular vesicles (EVs) are tiny biological nanovesicles ranging from approximately 30–
1000 nm in diameter that are released into the extracellular matrix of most cell types and in …

[HTML][HTML] Mitochondrial transfer and regulators of mesenchymal stromal cell function and therapeutic efficacy

A Mohammadalipour, SP Dumbali… - Frontiers in Cell and …, 2020 - frontiersin.org
Mesenchymal stromal cell (MSC) metabolism plays a crucial role in the microenvironment in
both normal physiology and disease. While MSCs predominantly utilize glycolysis in their …