There is growing evidence that excessive microglial phagocytosis of neurons and synapses
contributes to multiple brain pathologies. RNA‐seq and genome‐wide association (GWAS) …

Purpose Age‐related macular degeneration (AMD) is a degenerative disease of the macula,
often leading to progressive vision loss. The rate of disease progression can vary among …

Background Visual impairment in elderly people is a considerable health problem that
significantly affects quality of life of millions worldwide. The magnitude of this issue is …

Age-related diseases, including age-related macular degeneration (AMD), are of growing
importance in a world where population ageing has become a dominant global trend …

There is an urgency to find new treatment strategies that could prevent or delay the onset or
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …

Age-related macular degeneration (AMD) is a multifactorial disease influenced by a
combination of environmental factors and genetic variants. Genomic studies have been …

Retinal neurodegeneration is predominantly reported as the apoptosis or impaired function
of the photoreceptors. Retinal degeneration is a major causative factor of irreversible vision …

The pathophysiology of dry age-related macular degeneration (AMD) and specifically
geographic atrophy (GA) has been linked to the complement cascade. This cascade is part …

Age-related macular degeneration (AMD) is a leading cause of blindness. Genetic variants
at the chromosome 1q31. 3 encompassing the complement factor H (CFH, FH) and CFH …

Ischemic retinopathies (IRs), such as retinopathy of prematurity (ROP), diabetic retinopathy
(DR), and (in many cases) age‐related macular degeneration (AMD), are ocular disorders …