[HTML][HTML] Persistent breeding-induced endometritis in mares—A multifaceted challenge: From clinical aspects to immunopathogenesis and pathobiology

IF Canisso, LGTM Segabinazzi… - International journal of …, 2020 - mdpi.com
Post-breeding endometritis (ie, inflammation/infection of the endometrium), is a
physiological reaction taking place in the endometrium of mares within 48 h post-breeding …

[HTML][HTML] Equine endometritis: A review of challenges and new approaches

LHA Morris, PM McCue, C Aurich - Reproduction, 2020 - rep.bioscientifica.com
Endometritis in the mare begins as a normal physiological inflammatory response to
breeding that involves both a mechanical and immunological response pathway activated to …

[HTML][HTML] Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice

JE Schjenken, DJ Sharkey, ES Green, HY Chan… - Communications …, 2021 - nature.com
Seminal fluid factors modulate the female immune response at conception to facilitate
embryo implantation and reproductive success. Whether sperm affect this response has not …

[HTML][HTML] Sperm activate TLR2/TLR1 heterodimerization to induce a weak proinflammatory response in the bovine uterus

A Mansouri, MS Yousef, R Kowsar, N Usui… - Frontiers in …, 2023 - frontiersin.org
Toll-like receptor 2 (TLR2) signaling pathway is involved in the sperm-triggered uterine
inflammatory response at insemination, but its precise mechanism at molecular-level …

Sperm interactions with the female reproductive tract: A key for successful fertilization in mammals

M Saint-Dizier, C Mahe, K Reynaud, G Tsikis… - Molecular and Cellular …, 2020 - Elsevier
Sperm migration through the female genital tract is not a quiet journey. Uterine contractions
quickly operate a drastic selection, leading to a very restrictive number of sperm reaching …

Sperm enter glands of preovulatory bovine endometrial explants and initiate inflammation

I Akthar, SS Suarez, VA Morillo, M Sasaki… - …, 2020 - rep.bioscientifica.com
We previously reported that sperm binding to cultured monolayers of bovine uterine
epithelial cells induces an acute inflammatory response involving the Toll-like receptor …

[HTML][HTML] Sperm interaction with the uterine innate immune system: toll-like receptor 2 (TLR2) is a main sensor in cattle

I Akthar, MA Marey, Y Kim, M Shimada… - Reproduction …, 2021 - CSIRO Publishing
During the passage through the female reproductive tract, sperm interact with various
compartments and their immune systems. The immune system that protects the female …

[HTML][HTML] Conceptus-modulated innate immune function during early pregnancy in ruminants: a review

CC Rocha, JC Silveira, N Forde, M Binelli… - Animal …, 2021 - SciELO Brasil
This review focuses on the innate immune events modulated by conceptus signaling during
early pregnancy in ruminants. Interferon-tau (IFN-τ) plays a role in the recognition of …

Local action of cytokines and immune cells in communication between the conceptus and uterus during the critical period of early embryo development, attachment …

G Campanile, PS Baruselli, A Limone, JD Michael - Theriogenology, 2021 - Elsevier
Early embryo development, implantation and pregnancy involve a complex dialogue
between the embryo and mother. In cattle this dialogue starts as early as days 3–4 when the …

[HTML][HTML] The role of male reproductive tract secretions in ruminant fertility

B Fernandez-Fuertes - animal, 2023 - Elsevier
Male fertility largely depends on the ability to produce sperm that can transmit the paternal
information onto the next generation. However, the factors that are critical for sperm function …