[HTML][HTML] A systematic review of the association between dementia risk factors and cerebrovascular reactivity

C Wang, G Reid, CE Mackay, G Hayes, DP Bulte… - Neuroscience & …, 2023 - Elsevier
Cumulative evidence suggests that impaired cerebrovascular reactivity (CVR), a regulatory
response critical for maintaining neuronal health, is amongst the earliest pathological …

[HTML][HTML] Relationship between cerebrovascular reactivity and cognition among people with risk of cognitive decline

D Kim, TM Hughes, ME Lipford, S Craft… - Frontiers in …, 2021 - frontiersin.org
Vascular risk factors (eg, obesity and hypertension) are associated with cerebral small
vessel disease, Alzheimer's disease (AD) pathology, and dementia. Reduced perfusion may …

Older adults with higher blood pressure variability exhibit cerebrovascular reactivity deficits

IJ Sible, JY Jang, S Dutt, B Yew… - American Journal of …, 2023 - academic.oup.com
BACKGROUND Elevated blood pressure (BP) variability is predictive of increased risk for
stroke, cerebrovascular disease, and other vascular brain injuries, independent of …

[HTML][HTML] Contrasting measures of cerebrovascular reactivity between MRI and Doppler: a cross-sectional study of younger and older healthy individuals

CV Burley, ST Francis, KN Thomas… - Frontiers in …, 2021 - frontiersin.org
Cerebrovascular reactivity (CVR) is used as an outcome measure of brain health.
Traditionally, lower CVR is associated with ageing, poor fitness and brain-related conditions …

[HTML][HTML] ICA-based denoising strategies in breath-hold induced cerebrovascular reactivity mapping with multi echo BOLD fMRI

S Moia, M Termenon, E Uruñuela, G Chen… - Neuroimage, 2021 - Elsevier
Performing a BOLD functional MRI (fMRI) acquisition during breath-hold (BH) tasks is a non-
invasive, robust method to estimate cerebrovascular reactivity (CVR). However, movement …

[HTML][HTML] Breath-hold BOLD fMRI without CO2 sampling enables estimation of venous cerebral blood volume: potential use in normalization of stimulus-evoked BOLD …

E Biondetti, AM Chiarelli, M Germuska, I Lipp, A Villani… - NeuroImage, 2024 - Elsevier
BOLD fMRI signal has been used in conjunction with vasodilatory stimulation as a marker of
cerebrovascular reactivity (CVR): the relative change in cerebral blood flow (CBF) arising …

[HTML][HTML] Regional differences in the link between water exchange rate across the blood–brain barrier and cognitive performance in normal aging

V Zachariou, C Pappas, CE Bauer, X Shao, P Liu, H Lu… - GeroScience, 2024 - Springer
The blood–brain barrier (BBB) undergoes functional changes with aging which may
contribute to cognitive decline. A novel, diffusion prepared arterial spin labeling-based MRI …

Reduced and delayed cerebrovascular reactivity in patients with Parkinson's disease

SG Ryman, N Shaff, A Dodd, S Nitschke… - Movement …, 2023 - Wiley Online Library
Abstract Background Cerebrovascular dysfunction in Parkinson's disease (PD) is
heterogeneous and may contribute to disease pathophysiology or progression. There is a …

Influence of end‐tidal CO2 on cerebral blood flow during orthostatic stress in controls and adults with myalgic encephalomyelitis/chronic fatigue syndrome

CLMC van Campen, PC Rowe… - Physiological …, 2023 - Wiley Online Library
Brain perfusion is sensitive to changes in CO2 levels (CO2 reactivity). Previously, we
showed a pathological cerebral blood flow (CBF) reduction in the majority of myalgic …

[HTML][HTML] A practical modification to a resting state fMRI protocol for improved characterization of cerebrovascular function

RC Stickland, KM Zvolanek, S Moia, A Ayyagari… - Neuroimage, 2021 - Elsevier
Cerebrovascular reactivity (CVR), defined here as the Blood Oxygenation Level Dependent
(BOLD) response to a CO 2 pressure change, is a useful metric of cerebrovascular function …