Effect of visit-to-visit blood pressure variability on mild cognitive impairment and probable dementia in hypertensive patients receiving standard and intensive blood …

H Guo, Y Tan, Z Yao, Z Zhang, J Yan… - Frontiers in …, 2023 - frontiersin.org
Background High visit-to-visit blood pressure variability (BPV) and hypertension are risk
factors for mild cognitive impairment (MCI) and probable dementia (PD). Few articles …

Update on HD-Induced Multiorgan Ischemia: Brains and Beyond

CW McIntyre - Journal of the American Society of Nephrology, 2024 - journals.lww.com
Hemodialysis (HD) is a life-saving treatment for patients with kidney failure. However,
patients requiring HD have a 10-20 times higher risk of cardiovascular (CV) morbidity and …

[HTML][HTML] Multi-modal normalization of resting-state using local physiology reduces changes in functional connectivity patterns observed in mTBI patients

AA Champagne, NS Coverdale, A Ross, Y Chen… - NeuroImage: Clinical, 2020 - Elsevier
Blood oxygenation level dependent (BOLD) resting-state functional magnetic resonance
imaging (rs-fMRI) may serve as a sensitive marker to identify possible changes in the …

fMRI studies evaluating central respiratory control in humans

C Ciumas, S Rheims, P Ryvlin - Frontiers in Neural Circuits, 2022 - frontiersin.org
A plethora of neural centers in the central nervous system control the fundamental
respiratory pattern. This control is ensured by neurons that act as pacemakers, modulating …

Impaired cerebrovascular reactivity in pediatric sickle cell disease using diffuse correlation spectroscopy

KR Cowdrick, M Akbar, T Boodooram… - Biomedical Optics …, 2023 - opg.optica.org
Cerebrovascular reactivity (CVR), defined as the ability of cerebral vasculature to dilate in
response to a vasodilatory stimulus, is an integral mechanism in brain homeostasis that is …

Metabolic remodelling of mice by hypoxic-hypercapnic environment: imitating the naked mole-rat

DA Tolstun, A Knyazer, TV Tushynska, TA Dubiley… - Biogerontology, 2020 - Springer
We hypothesised that hypoxic-hypercapnic environment (HHE) could induce metabolic
suppression and associated benefits for health and longevity, as observed in the naked …

Compromised resting cerebral metabolism after sport-related concussion: a calibrated MRI study

AA Champagne, NS Coverdale… - Brain imaging and …, 2021 - Springer
Altered resting cerebral blood flow (CBF 0) in the acute phase post-concussion may
contribute to neurobehavioral deficiencies, often reported weeks after the injury. However, in …

Multi-parametric analysis reveals metabolic and vascular effects driving differences in BOLD-based cerebrovascular reactivity associated with a history of sport …

AA Champagne, NS Coverdale, M Germuska… - Brain injury, 2019 - Taylor & Francis
Objective: Identify alterations in cerebrovascular reactivity (CVR) based on the history of
sport-related concussion (SRC). Further explore possible mechanisms underlying …

Impaired cerebrovascular reactivity in Huntington's disease

ST Chan, ND Mercaldo, KK Kwong, SM Hersch… - Frontiers in …, 2021 - frontiersin.org
There is increasing evidence that impairments of cerebrovascular function and/or
abnormalities of the cerebral vasculature might contribute to early neuronal cell loss in …

Quantification of cerebral perfusion and cerebrovascular reserve using Turbo‐QUASAR arterial spin labeling MRI

MY Zhao, L Václavů, ET Petersen… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To compare cerebral blood flow (CBF) and cerebrovascular reserve (CVR)
quantification from Turbo‐QUASAR (quantitative signal targeting with alternating …