Nutrition in chronic inflammatory conditions: bypassing the mucosal block for micronutrients

F Roth‐Walter, R Berni Canani, L O'Mahony, D Peroni… - Allergy, 2024 - Wiley Online Library
Nutritional Immunity is one of the most ancient innate immune responses, during which the
body can restrict nutrients availability to pathogens and restricts their uptake by the gut …

The connection between epigenetics and gut microbiota‐current perspective

X Yuan, Y Tan, O Bajinka, ML Jammeh… - Cell Biochemistry …, 2024 - Wiley Online Library
Both the epigenetic changes and gut microbiota (GM) have attracted a growing interest in
establishing effective diagnostics and potential therapeutic strategies for a number of …

iPSC-Derived Astrocytes and Neurons Replicate Brain Gene Expression, Epigenetic, Cell Morphology and Connectivity Alterations Found in Autism

H Mostafavi Abdolmaleky, R Alam, S Nohesara… - Cells, 2024 - mdpi.com
Excessive inflammatory reactions and oxidative stress are well-recognized molecular
findings in autism and these processes can affect or be affected by the epigenetic …

The Embodied Microbiome

RR Dietert, JM Dietert - 2023 - preprints.org
Microbes are the most prevalent and widely-distributed life form on planet Earth. They are
also cognitive organisms with memory and superior problem-solving skills that use quantum …

[HTML][HTML] The Effect of Maternal High-Fat or High-Carbohydrate Diet during Pregnancy and Lactation on Cytochrome P450 2D (CYP2D) in the Liver and Brain of Rat …

W Kuban, A Haduch, E Bromek… - International Journal of …, 2024 - mdpi.com
Cytochrome P450 2D (CYP2D) is important in psychopharmacology as it is engaged in the
metabolism of drugs, neurosteroids and neurotransmitters. An unbalanced maternal diet …

Potential for New Therapeutic Approaches by Targeting Lactate and pH Mediated Epigenetic Dysregulation in Major Mental Diseases

S Nohesara, HM Abdolmaleky, S Thiagalingam - Biomedicines, 2024 - mdpi.com
Multiple lines of evidence have shown that lactate-mediated pH alterations in the brains of
patients with neuropsychiatric diseases such as schizophrenia (SCZ), Alzheimer's disease …

Epigenome Defines Aberrant Brain Laterality in Major Mental Illnesses

HM Abdolmaleky, S Nohesara, S Thiagalingam - Brain Sciences, 2024 - mdpi.com
Brain-hemisphere asymmetry/laterality is a well-conserved biological feature of normal brain
development. Several lines of evidence, confirmed by the meta-analysis of different studies …

Methylation of SSTR4 promoter region in multiple mental health disorders

R Zhao, H Shi, Y Wang, S Zheng, Y Xu - Frontiers in Genetics, 2024 - frontiersin.org
The existence of a shared genetic basis for mental disorders has long been documented, yet
research on whether acquired epigenetic modifications exhibit common alterations across …

[HTML][HTML] Microbiome and Long-Term Health Considerations

JO Zavala-Soto - 2024 - intechopen.com
All the tissues of our body are formed by cells, but there are at least 1–10 times more
microbes than cells in it, which coexist in balance and help us maintain our health. Most of …

The prenatal nicotine exposure leads to epigenetic alterations in nervous system signaling genes in the rat

JAM Muriel, O Dali, AV Baco, S Tevosian, LF Hayward… - 2024 - researchsquare.com
Background. Prenatal nicotine exposure (PNE) has been documented to impose numerous
deleterious effects on fetal development. However, the epigenetic changes promoted by …