The mechanism and therapy of aortic aneurysms
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …
Novel pharmacological approaches in abdominal aortic aneurysm
L Puertas-Umbert, R Almendra-Pegueros… - Clinical …, 2023 - portlandpress.com
Abdominal aortic aneurysm (AAA) is a severe vascular disease and a major public health
issue with an unmet medical need for therapy. This disease is featured by a progressive …
issue with an unmet medical need for therapy. This disease is featured by a progressive …
Exosomal miR-17-5p from adipose-derived mesenchymal stem cells inhibits abdominal aortic aneurysm by suppressing TXNIP-NLRP3 inflammasome
J Hu, Y Jiang, X Wu, Z Wu, J Qin, Z Zhao, B Li… - Stem Cell Research & …, 2022 - Springer
Background Preclinical studies have suggested that adipose-derived mesenchymal stem
cells (ADSCs) transplantation can suppress abdominal aortic inflammation and aneurysm …
cells (ADSCs) transplantation can suppress abdominal aortic inflammation and aneurysm …
Pathogenesis-guided rational engineering of nanotherapies for the targeted treatment of abdominal aortic aneurysm by inhibiting neutrophilic inflammation
K Hu, L Zhong, W Lin, G Zhao, W Pu, Z Feng, M Zhou… - ACS …, 2024 - ACS Publications
Abdominal aortic aneurysm (AAA) remains a fatal disease in the elderly. Currently, no drugs
can be clinically used for AAA therapy. Considering the pivotal role of neutrophils in the …
can be clinically used for AAA therapy. Considering the pivotal role of neutrophils in the …
Management of endoleaks after elective infrarenal aortic endovascular aneurysm repair: a review
Importance Endovascular aneurysm repair (EVAR) is the dominant treatment strategy for
abdominal aortic aneurysms, encompassing 80% of all repairs in the United States …
abdominal aortic aneurysms, encompassing 80% of all repairs in the United States …
The circular RNA Ataxia Telangiectasia Mutated regulates oxidative stress in smooth muscle cells in expanding abdominal aortic aneurysms
An abdominal aortic aneurysm (AAA) is a pathological widening of the aortic wall
characterized by loss of smooth muscle cells (SMCs), extracellular matrix degradation, and …
characterized by loss of smooth muscle cells (SMCs), extracellular matrix degradation, and …
A Multi‐Bioactive Nanomicelle‐Based “One Stone for Multiple Birds” Strategy for Precision Therapy of Abdominal Aortic Aneurysms
W Lin, K Hu, C Li, W Pu, X Yan, H Chen… - Advanced …, 2022 - Wiley Online Library
Abdominal aortic aneurysm (AAA) remains a lethal aortic disease in the elderly. Currently,
no effective drugs can be clinically applied to prevent the development of AAA. Herein, a …
no effective drugs can be clinically applied to prevent the development of AAA. Herein, a …
Early Progression of Abdominal Aortic Aneurysm is Decelerated by Improved Endothelial Barrier Function via ALDH2‐LIN28B‐ELK3 Signaling
K Yang, S Cui, J Wang, T Xu, H Du, H Yue… - Advanced …, 2023 - Wiley Online Library
The involvement of endothelial barrier function in abdominal aortic aneurysm (AAA) and its
upstream regulators remains unknown. Single‐cell RNA sequencing shows that disrupted …
upstream regulators remains unknown. Single‐cell RNA sequencing shows that disrupted …
Association between the non-HDL-cholesterol to HDL-cholesterol ratio and abdominal aortic aneurysm from a Chinese screening program
W Lin, S Luo, W Li, J Liu, T Zhou, F Yang… - Lipids in Health and …, 2023 - Springer
Abstract Background Abdominal aortic aneurysms (AAAs) can result in high mortality upon
rupture but are usually undiagnosed because of the absence of symptoms in the early stage …
rupture but are usually undiagnosed because of the absence of symptoms in the early stage …
[HTML][HTML] Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication
K Huang, Y Wu, Y Zhang, JY Youn, H Cai - Redox Biology, 2022 - Elsevier
Aortic aneurysms are prevalent and severe vascular diseases with high mortality from
unpredicted ruptures, while the only treatment option is surgical correction of large …
unpredicted ruptures, while the only treatment option is surgical correction of large …