Cell fate specification and differentiation in the adult mammalian intestine

J Beumer, H Clevers - Nature reviews Molecular cell biology, 2021 - nature.com
Intestinal stem cells at the bottom of crypts fuel the rapid renewal of the different cell types
that constitute a multitasking tissue. The intestinal epithelium facilitates selective uptake of …

DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …

Mitochondrial function in spinal cord injury and regeneration

PG Slater, ME Domínguez-Romero, M Villarreal… - Cellular and Molecular …, 2022 - Springer
Many people around the world suffer from some form of paralysis caused by spinal cord
injury (SCI), which has an impact on quality and life expectancy. The spinal cord is part of …

Epigenetic regulation of genomic stability by vitamin C

JP Brabson, T Leesang, S Mohammad… - Frontiers in genetics, 2021 - frontiersin.org
DNA methylation plays an important role in the maintenance of genomic stability. Ten-
eleven translocation proteins (TETs) are a family of iron (Fe2+) and α-KG-dependent …

Emerging risk of environmental factors: insight mechanisms of Alzheimer's diseases

MA Rahman, MS Rahman, MJ Uddin… - … Science and Pollution …, 2020 - Springer
Neurodegenerative disorders are typically sporadic in nature in addition to usually
influenced through an extensive range of environmental factors, lifestyle, and genetic …

DNA methylation in thyroid cancer

C Zafon, J Gil, B Pérez-González… - Endocrine-related …, 2019 - erc.bioscientifica.com
In recent years, cancer genomics has provided new insights into genetic alterations and
signaling pathways involved in thyroid cancer. However, the picture of the molecular …

Mechanisms of plant epigenetic regulation in response to plant stress: Recent discoveries and implications

MI Abdulraheem, Y Xiong, AY Moshood… - Plants, 2024 - mdpi.com
Plant stress is a significant challenge that affects the development, growth, and productivity
of plants and causes an adverse environmental condition that disrupts normal physiological …

Epigenetic regulation of cancer stem cell formation and maintenance

R French, S Pauklin - International journal of cancer, 2021 - Wiley Online Library
Cancerous tumours contain a rare subset of cells with stem‐like properties that are termed
cancer stem cells (CSCs). CSCs are defined by their ability to divide both symmetrically and …

Genome-scale methylation analysis identifies immune profiles and age acceleration associations with bladder cancer outcomes

JQ Chen, LA Salas, JK Wiencke, DC Koestler… - … Biomarkers & Prevention, 2023 - AACR
Background: Immune profiles have been associated with bladder cancer outcomes and may
have clinical applications for prognosis. However, associations of detailed immune cell …

Prenatal epigenetics diets play protective roles against environmental pollution

S Li, M Chen, Y Li, TO Tollefsbol - Clinical epigenetics, 2019 - Springer
It is thought that germ cells and preimplantation embryos during development are most
susceptible to endogenous and exogenous environmental factors because the epigenome …