Lipid droplets (LDs), which are active organelles, derive from the monolayer membrane of
the endoplasmic reticulum and encapsulate neutral lipids internally. LD-associated proteins …

Skeletal system-related diseases, such as osteoporosis, arthritis, osteosarcoma and
sarcopenia, are becoming major public health concerns. These diseases are characterized …

Urolithin A (UA) has demonstrated the ability to stimulate mitophagy and enhance
mitochondrial and cellular health in skeletal muscles in humans after oral administration. It is …

Ubiquitination is a major posttranslational covalent modification that regulates numerous
cellular processes including inflammasome signaling. Cells also contain unanchored …

We here show that SNX10 localizes to endocytic compartments in a PtdIns3P-dependent
manner and that mutations in the PX domain associated with autosomal recessive …