Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Skeletal muscle is a crucial tissue for movement, gestural assistance, metabolic
homeostasis, and thermogenesis. It makes up approximately 40% of the total body weight …

Exercise has long been known for its active role in improving physical fitness and sustaining
health. Regular moderate-intensity exercise improves all aspects of human health and is …

Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

There is a significant interest in identifying blood-borne factors that mediate tissue crosstalk
and function as molecular effectors of physical activity. Although past studies have focused …

Background Age‐associated sarcopenia is characterized of progressed loss of skeletal
muscle power, mass, and function, which affects human physical activity and life quality …

Exercise mimetics are a proposed class of therapeutics that specifically mimic or enhance
the therapeutic effects of exercise. Increased physical activity has demonstrated positive …

The obesity epidemic shows no signs of abatement. Genetics and overnutrition together with
a dramatic decline in physical activity are the alleged main causes for this pandemic. While …

Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …

The risk associated with multiple cancers, cardiovascular disease, diabetes, and all-cause
mortality is decreased in individuals who meet the current recommendations for physical …