[HTML][HTML] HERVs and cancer—A comprehensive review of the relationship of human endogenous retroviruses and human cancers

E Stricker, EC Peckham-Gregory, ME Scheurer - Biomedicines, 2023 - mdpi.com
Genomic instability and genetic mutations can lead to exhibition of several cancer hallmarks
in affected cells such as sustained proliferative signaling, evasion of growth suppression …

[HTML][HTML] Human endogenous retrovirus K contributes to a stem cell niche in glioblastoma

AH Shah, SR Rivas, TT Doucet-O'Hare… - The Journal of …, 2023 - Am Soc Clin Investig
Human endogenous retroviruses (HERVs) are ancestral viral relics that constitute nearly 8%
of the human genome. Although normally silenced, the most recently integrated provirus …

[HTML][HTML] Cell Fusion-related proteins and signaling pathways, and their roles in the development and progression of cancer

H Zhang, H Ma, X Yang, L Fan, S Tian, R Niu… - Frontiers in Cell and …, 2022 - frontiersin.org
Cell fusion is involved in many physiological and pathological processes, including gamete
binding, and cancer development. The basic processes of cell fusion include membrane …

[HTML][HTML] Integrated systems biology approach identifies novel maternal and placental pathways of preeclampsia

NG Than, R Romero, AL Tarca, KA Kekesi… - Frontiers in …, 2018 - frontiersin.org
Preeclampsia is a disease of the mother, fetus, and placenta, and the gaps in our
understanding of the complex interactions among their respective disease pathways …

[HTML][HTML] Identification of inflammatory subgroups of schizophrenia and bipolar disorder patients with HERV-W ENV antigenemia by unsupervised cluster analysis

R Tamouza, U Meyer, M Foiselle, JR Richard… - Translational …, 2021 - nature.com
Human endogenous retroviruses (HERVs) are remnants of infections that took place several
million years ago and represent around 8% of the human genome. Despite evidence …

[HTML][HTML] Type W human endogenous retrovirus (HERV-W) integrations and their mobilization by L1 machinery: contribution to the human transcriptome and impact on …

N Grandi, E Tramontano - Viruses, 2017 - mdpi.com
Human Endogenous Retroviruses (HERVs) are ancient infection relics constituting~ 8% of
our DNA. While HERVs' genomic characterization is still ongoing, impressive amounts of …

[HTML][HTML] Syncytin-1 nonfusogenic activities modulate inflammation and contribute to preeclampsia pathogenesis

C Bu, Z Wang, Y Ren, D Chen, SW Jiang - Cellular and Molecular Life …, 2022 - Springer
Maternal cellular and humoral immune responses to the allogeneic fetoplacental unit are a
normal part of pregnancy adaptation. Overactive or dysregulated immune responses that …

[HTML][HTML] Neurological soft signs in schizophrenia: an update on the state-versus trait-perspective

S Bachmann, J Schröder - Frontiers in psychiatry, 2018 - frontiersin.org
Background Neurological soft signs (NSS) represent minor neurological signs, which
indicate non-specific cerebral dysfunction. In schizophrenia, their presence has been …

[HTML][HTML] Do human endogenous retroviruses contribute to multiple sclerosis, and if so, how?

G Morris, M Maes, M Murdjeva, BK Puri - Molecular Neurobiology, 2019 - Springer
The gammaretroviral human endogenous retrovirus (HERV) families MRSV/HERV-W and
HERV-H (including the closely related HERV-Fc1) are associated with an increased risk of …

Contribution of syncytins and other endogenous retroviral envelopes to human placenta pathologies

PA Bolze, M Mommert, F Mallet - Progress in Molecular Biology and …, 2017 - Elsevier
Fusion, proliferation, angiogenesis, immune tolerance, and tissue survival are some of the
critical functions involved in the physiological and pathological processes of placenta …