Sp1 and the 'hallmarks of cancer'

K Beishline, J Azizkhan‐Clifford - The FEBS journal, 2015 - Wiley Online Library
For many years, transcription factor Sp1 was viewed as a basal transcription factor and
relegated to a role in the regulation of so‐called housekeeping genes. Identification of Sp1's …

The effects of early life stress on the epigenome: from the womb to adulthood and even before

N Provençal, EB Binder - Experimental neurology, 2015 - Elsevier
Exposure to early life stress (ELS), such as childhood abuse and neglect is a well
established major risk factor for developing psychiatric and behavioral disorders later in life …

Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA

M Wang, C Mao, L Ouyang, Y Liu, W Lai, N Liu… - Cell Death & …, 2019 - nature.com
The regulatory loop between long noncoding RNAs (lncRNAs) and microRNAs has a
dynamic role in transcriptional and translational regulation, and is involved in cancer …

[HTML][HTML] EGLN1/c-Myc induced lymphoid-specific helicase inhibits ferroptosis through lipid metabolic gene expression changes

Y Jiang, C Mao, R Yang, B Yan, Y Shi, X Liu, W Lai… - Theranostics, 2017 - ncbi.nlm.nih.gov
Ferroptosis is a newly discovered form of non-apoptotic cell death in multiple human
diseases. However, the epigenetic mechanisms underlying ferroptosis remain poorly …

DNA methylation: shared and divergent features across eukaryotes

RJ Schmitz, ZA Lewis, MG Goll - Trends in Genetics, 2019 - cell.com
Chemical modification of nucleotide bases in DNA provides one mechanism for conveying
information in addition to the genetic code. 5-methylcytosine (5mC) represents the most …

The developmental origins of chronic physical aggression: biological pathways triggered by early life adversity

N Provençal, L Booij… - Journal of Experimental …, 2015 - journals.biologists.com
Longitudinal epidemiological studies with birth cohorts have shown that physical aggression
in humans does not appear suddenly in adolescence as commonly thought. In fact …

[图书][B] Epigenetics

L Armstrong - 2020 - taylorfrancis.com
The concept of epigenetics has been known about since the 1940s, but it is only in the last
10 years that research has shown just how wide ranging its effects are. It is now a very …

An electrochemical strategy with tetrahedron rolling circle amplification for ultrasensitive detection of DNA methylation

H Liu, J Luo, L Fang, H Huang, J Deng, J Huang… - Biosensors and …, 2018 - Elsevier
Sensitive and specific detection of DNA methylation in genomic DNA is imperative for rapid
epigenetic evaluations. Here, a novel sensitive electrochemical strategy was developed for …

PKM2: the thread linking energy metabolism reprogramming with epigenetics in cancer

L Chen, Y Shi, S Liu, Y Cao, X Wang, Y Tao - International journal of …, 2014 - mdpi.com
Cancer metabolism reprogramming or alterations in epigenetics are linked to an incidence
of cancer. It is apparent that epigenetic changes have been found in tumors, therefore, the …

IncRNA AK017368 promotes proliferation and suppresses differentiation of myoblasts in skeletal muscle development by attenuating the function of miR‐30c

T Liang, B Zhou, L Shi, H Wang, Q Chu, F Xu… - The FASEB …, 2018 - Wiley Online Library
Long noncoding RNAs (lncRNAs) have been reported to play diverse roles in biologic and
pathologic processes, including myogenesis. We found that lncRNA AK017368 is highly …