Overcoming challenges and dogmas to understand the functions of pseudogenes
Pseudogenes are defined as regions of the genome that contain defective copies of genes.
They exist across almost all forms of life, and in mammalian genomes are annotated in …
They exist across almost all forms of life, and in mammalian genomes are annotated in …
The genetics and epigenetics of 22q11. 2 deletion syndrome
Q Du, MT de la Morena, NSC van Oers - Frontiers in Genetics, 2020 - frontiersin.org
Chromosome 22q11. 2 deletion syndrome (22q11. 2del) is a complex, multi-organ disorder
noted for its varying severity and penetrance among those affected. The clinical problems …
noted for its varying severity and penetrance among those affected. The clinical problems …
MicroRNAs, long noncoding RNAs, and circular RNAs: potential tumor biomarkers and targets for colorectal cancer
S Yang, Z Sun, Q Zhou, W Wang, G Wang… - Cancer management …, 2018 - Taylor & Francis
Noncoding RNAs (ncRNAs) can be divided into microRNAs (miRNAs), long noncoding
RNAs (lncRNAs), circular RNAs (circRNAs), pRNAs, and tRNAs. Traditionally, miRNAs exert …
RNAs (lncRNAs), circular RNAs (circRNAs), pRNAs, and tRNAs. Traditionally, miRNAs exert …
Pseudogenes as functionally significant elements of the genome
TF Kovalenko, LI Patrushev - Biochemistry (Moscow), 2018 - Springer
Pseudogene is a gene copy that has lost its original function. For a long time, pseudogenes
have been considered as “junk DNA” that inevitably arises as a result of ongoing …
have been considered as “junk DNA” that inevitably arises as a result of ongoing …
LncRNA EBLN3P promotes the progression of osteosarcoma through modifying the miR-224-5p/Rab10 signaling axis
S Dai, N Li, M Zhou, Y Yuan, D Yue, T Li, X Zhang - Scientific Reports, 2021 - nature.com
The treatment of patients with advanced-stage osteosarcoma represents a major challenge,
with very few treatments currently approved. Although accumulating evidence has …
with very few treatments currently approved. Although accumulating evidence has …
The world of pseudogenes: new diagnostic and therapeutic targets in cancers or still mystery molecules?
M Stasiak, T Kolenda, J Kozłowska-Masłoń… - Life, 2021 - mdpi.com
Pseudogenes were once considered as “junk DNA”, due to loss of their functions as a result
of the accumulation of mutations, such as frameshift and presence of premature stop-codons …
of the accumulation of mutations, such as frameshift and presence of premature stop-codons …
Identification and expression analysis of long noncoding RNAs in fat-tail of sheep breeds
MR Bakhtiarizadeh, SA Salami - G3: Genes, Genomes …, 2019 - academic.oup.com
Emerging evidence suggests that long non-coding RNAs (lncRNAs) participate in the
regulation of a diverse range of biological processes. However, most studies have been …
regulation of a diverse range of biological processes. However, most studies have been …
HAR1: An Insight Into lncRNA Genetic Evolution
Long noncoding RNAs (lncRNAs) have a wide range of functions in health and disease, but
many remain uncharacterized because of their complex expression patterns and structures …
many remain uncharacterized because of their complex expression patterns and structures …
A family of long intergenic non-coding RNA genes in human chromosomal region 22q11. 2 carry a DNA translocation breakpoint/AT-rich sequence
N Delihas - PLoS One, 2018 - journals.plos.org
FAM230C, a long intergenic non-coding RNA (lincRNA) gene in human chromosome 13
(chr13) is a member of lincRNA genes termed family with sequence similarity 230. An …
(chr13) is a member of lincRNA genes termed family with sequence similarity 230. An …
[HTML][HTML] Long noncoding RNAs are associated with metabolic and cellular processes in the jejunum mucosa of pre-weaning calves in response to different diets
R Weikard, F Hadlich, HM Hammon, D Frieten… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Long noncoding RNAs are associated with metabolic and cellular processes in the jejunum
mucosa of pre-weaning calves in response to different diets - PMC Back to Top Skip to main …
mucosa of pre-weaning calves in response to different diets - PMC Back to Top Skip to main …