Cardiac amyloidosis is a form of restrictive infiltrative cardiomyopathy that confers significant
mortality. Due to the relative rarity of cardiac amyloidosis, clinical and diagnostic expertise in …

Multiple myeloma (MM) is a plasma cell neoplasm that accounts for 2% of all haematological
malignancies and predominantly affects older individuals (with a median age at diagnosis of …

Sharmila Dorbala, MD, MPH, FASNC, Chair*; Yukio Ando, MD, PhD†; Sabahat Bokhari,
MD‡; Angela Dispenzieri, MD § ; Rodney H. Falk, MD*; Victor A. Ferrari, MD∥; Marianna …

Background Patients with precursors to multiple myeloma are dichotomised as having
monoclonal gammopathy of undetermined significance or smouldering multiple myeloma on …

AL amyloidosis results from clonal production of immunoglobulin light chains, most
commonly arising from a clonal plasma cell disorder. Once considered a nearly uniformly …

Recent years have witnessed a rapid growth in our understanding of the pathogenic
property of monoclonal proteins. It is evident that some of these small monoclonal proteins …

This Review outlines a practical approach to assessing and managing polyclonal
hypergammaglobulinaemia in adults. Polyclonal hypergammaglobulinaemia is most …

Amyloidosis refers to an etiologically heterogeneous group of protein misfolding diseases,
pathologically characterized by extracellular amyloid fibrils producing congophillic …

Multiple myeloma (MM) is a plasma cell (PC) malignancy of terminally differentiated B
lymphocytes that is typically associated with the secretion of partial and/or complete …

Objective Parotid swelling (PSW) is a major predictor of non-Hodgkin's lymphoma (NHL) in
primary SS (pSS). However, since detailed information on the time of onset and duration of …