Melanoma is one of the most aggressive forms of skin cancer, with few possibilities for
therapeutic approaches, due to its multi-drug resistance and, consequently, low survival rate …

The emergence of drug resistance in pathogenic bacteria due to the indiscriminate use of
antibiotics is a major challenge to global public health. Therefore, improved and more …

Melanoma is one of the most aggressive forms of skin cancer, with limited therapeutic
options. Since its incidence has been rapidly rising in recent years, the study of new targeted …

Due to the inability of the BBB to carry the drug into the brain, targeting drugs to the brain is
one of the most challenging issues. Various invasive and non-invasive methods have been …

Abstract The 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay is
the most common method for the determination of cell toxicity, but some factors limit the …

We report here the synthesis of novel thymine biomimetic photo-adducts bearing an alkane
spacer between nucleobases and characterized by antimelanoma activity against two …

Recent preclinical and clinical studies have focused on the active area of therapeutic
peptides due to their high potency, selectivity, and specificity in treating a broad range of …

Chronic exposure to ultraviolet (UV) radiation is known to induce the formation of DNA photo-
adducts, including cyclobutane pyrimidine dimers (CPDs) and Dewar valence derivatives …

Trimethylchlorosilane silylated silica aerogel (TS-SA) was loaded with a model drug, aspirin.
TS-SA preparation, drug loading, and drying were performed through ambient pressure …

Kajian ini dilakukan untuk mengkaji kesan tindak balas nanozarah polimer, silika dioksida
(SiO2) dengan protein,(Lisozim) dalam larutan penimbal. Tujuan kajian adalah untuk …