Recent progress in epigenetics of obesity

FY Wu, RX Yin - Diabetology & Metabolic Syndrome, 2022 - Springer
Nowadays, obesity is one of the largest public health problems worldwide. In the last few
decades, there has been a marked increase in the obesity epidemic and its related …

Epigenetic reprogramming in metabolic disorders: nutritional factors and beyond

Z Cheng, L Zheng, FA Almeida - The Journal of nutritional biochemistry, 2018 - Elsevier
Environmental factors (eg, malnutrition and physical inactivity) contribute largely to
metabolic disorders including obesity, type 2 diabetes, cardiometabolic disease and …

Impact of consuming extra-virgin olive oil or nuts within a Mediterranean diet on DNA methylation in peripheral white blood cells within the PREDIMED-Navarra …

A Arpón, FI Milagro, C Razquin, D Corella, R Estruch… - Nutrients, 2017 - mdpi.com
DNA methylation could be reversible and mouldable by environmental factors, such as
dietary exposures. The objective was to analyse whether an intervention with two …

Perspectives and challenges of epigenetic determinants of childhood obesity: a systematic review

R Alfano, O Robinson, E Handakas, TS Nawrot… - Obesity …, 2022 - Wiley Online Library
The tremendous increase in childhood obesity prevalence over the last few decades cannot
merely be explained by genetics and evolutionary changes in the genome, implying that …

DNA-methylation and body composition in preschool children: epigenome-wide-analysis in the European Childhood Obesity Project (CHOP)-Study

P Rzehak, M Covic, R Saffery, E Reischl, S Wahl… - Scientific reports, 2017 - nature.com
Adiposity and obesity result from the interaction of genetic variation and environmental
factors from very early in life, possibly mediated by epigenetic processes. Few Epigenome …

A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids

MA Jhun, M Mendelson, R Wilson, R Gondalia… - Nature …, 2021 - nature.com
Here we examine the association between DNA methylation in circulating leukocytes and
blood lipids in a multi-ethnic sample of 16,265 subjects. We identify 148, 35, and 4 novel …

Examining the association between adiposity and DNA methylation: a systematic review and meta‐analysis

WL Do, J Gohar, LE McCullough, KI Galaviz… - Obesity …, 2021 - Wiley Online Library
Obesity is associated with widespread differential DNA methylation (DNAm) patterns, though
there have been limited overlap in the obesity‐associated cytosine–guanine nucleotide pair …

Obesity-related epigenetic changes after bariatric surgery

AG Izquierdo, AB Crujeiras - Frontiers in endocrinology, 2019 - frontiersin.org
Objective: In recent years, an increasing number of studies have begun focusing on
epigenetics as a link between environmental factors and a greater predisposition to the …

Body mass index is associated with epigenetic age acceleration in the visceral adipose tissue of subjects with severe obesity

J de Toro-Martín, F Guénard, A Tchernof, FS Hould… - Clinical …, 2019 - Springer
Background There is solid evidence that obesity induces the acceleration of liver epigenetic
aging. However, unlike easily accessible blood or subcutaneous adipose tissue, little is …

[HTML][HTML] Epigenetic effects of healthy foods and lifestyle habits from the Southern European Atlantic Diet pattern: a narrative review

PM Lorenzo, AG Izquierdo, G Rodriguez-Carnero… - Advances in …, 2022 - Elsevier
Recent scientific evidence has shown the importance of diet and lifestyle habits for the
proper functioning of the human body. A balanced and healthy diet, physical activity, and …