Antigen presentation lies at the heart of immune recognition of infected or malignant cells.
For this reason, important efforts have been made to predict which peptides are more likely …

The immunopeptidome is the set of peptides presented by the major histocompatibility
complex (MHC) molecules, in humans also known as the human leukocyte antigen (HLA) …

Computational prediction of the peptides presented on major histocompatibility complex
(MHC) class I proteins is an important tool for studying T cell immunity. The data available to …

Post-translational modification (PTM) of antigens provides an additional source of
specificities targeted by immune responses to tumors or pathogens, but identifying antigen …

Profound global loss of DNA methylation is a hallmark of many cancers. One potential
consequence of this is the reactivation of transposable elements (TEs) which could stimulate …

The precise identification of Human Leukocyte Antigen class I (HLA-I) binding motifs plays a
central role in our ability to understand and predict (neo-) antigen presentation in infectious …

We analyze transposable elements (TEs) in glioblastoma (GBM) patients using a
proteogenomic pipeline that combines single-cell transcriptomics, bulk RNA sequencing …

Most high-grade serous ovarian cancer (HGSOC) patients develop resistance to platinum-
based chemotherapy and recur, but 15% remain disease free over a decade. To discover …

The entirety of human leukocyte antigen (HLA)‐presented peptides is referred to as the HLA
ligandome of a cell or tissue, in tumours often termed immunopeptidome. Mapping the …

The set of peptides presented on a cell's surface by MHC molecules is known as the
immunopeptidome. Current mass spectrometry technologies allow for identification of large …