POZ for effect–POZ-ZF transcription factors in cancer and development
KF Kelly, JM Daniel - Trends in cell biology, 2006 - cell.com
The BTB/POZ-ZF [Broad complex, Tramtrack, Bric à brac (BTB) or poxvirus and zinc finger
(POZ)-zinc finger] protein family comprises a diverse group of transcription factors. POZ-ZF …
(POZ)-zinc finger] protein family comprises a diverse group of transcription factors. POZ-ZF …
Kaiso/p120-catenin and TCF/β-catenin complexes coordinately regulate canonical Wnt gene targets
J Park, SW Kim, JP Lyons, H Ji, TT Nguyen, K Cho… - Developmental cell, 2005 - cell.com
Summary β-catenin-dependent or canonical Wnt signals are fundamental in animal
development and tumor progression. Using Xenopus laevis, we report that the BTB/POZ zinc …
development and tumor progression. Using Xenopus laevis, we report that the BTB/POZ zinc …
Beyond β-catenin: prospects for a larger catenin network in the nucleus
PD McCrea, CJ Gottardi - Nature reviews Molecular cell biology, 2016 - nature.com
Abstract β-catenin is widely regarded as the primary transducer of canonical WNT signals to
the nucleus. In most vertebrates, there are eight additional catenins that are structurally …
the nucleus. In most vertebrates, there are eight additional catenins that are structurally …
LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression
HT Aung, K Schroder, SR Himes, K Brion… - The FASEB …, 2006 - Wiley Online Library
Bacterial LPS triggers dramatic changes in gene expression in macrophages. We show here
that LPS regulated several members of the histone deacetylase (HDAC) family at the mRNA …
that LPS regulated several members of the histone deacetylase (HDAC) family at the mRNA …
Multiple roles of class I HDACs in proliferation, differentiation, and development
N Reichert, MA Choukrallah, P Matthias - Cellular and Molecular Life …, 2012 - Springer
Abstract Class I Histone deacetylases (HDACs) play a central role in controlling cell cycle
regulation, cell differentiation, and tissue development. These enzymes exert their function …
regulation, cell differentiation, and tissue development. These enzymes exert their function …
[HTML][HTML] Nuclear hormone receptor co-repressors: structure and function
PJ Watson, L Fairall, JWR Schwabe - Molecular and cellular endocrinology, 2012 - Elsevier
Co-repressor proteins, such as SMRT and NCoR, mediate the repressive activity of
unliganded nuclear receptors and other transcription factors. They appear to act as …
unliganded nuclear receptors and other transcription factors. They appear to act as …
Physiological roles of class I HDAC complex and histone demethylase
T Hayakawa, J Nakayama - BioMed Research International, 2011 - Wiley Online Library
Epigenetic gene silencing is one of the fundamental mechanisms for ensuring proper gene
expression patterns during cellular differentiation and development. Histone deacetylases …
expression patterns during cellular differentiation and development. Histone deacetylases …
Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery
J Oberoi, L Fairall, PJ Watson, JC Yang… - Nature structural & …, 2011 - nature.com
Eukaryotic transcriptional repressors function by recruiting large coregulatory complexes
that target histone deacetylase enzymes to gene promoters and enhancers. Transcriptional …
that target histone deacetylase enzymes to gene promoters and enhancers. Transcriptional …
Gallic acid suppresses lipopolysaccharide-induced nuclear factor-κB signaling by preventing RelA acetylation in A549 lung cancer cells
KC Choi, YH Lee, MG Jung, SH Kwon, MJ Kim… - Molecular Cancer …, 2009 - AACR
Although multiple studies have revealed that gallic acid plays an important role in the
inhibition of malignant transformation, cancer development, and inflammation, the molecular …
inhibition of malignant transformation, cancer development, and inflammation, the molecular …
Coronin 2A mediates actin-dependent de-repression of inflammatory response genes
Toll-like receptors (TLRs) function as initiators of inflammation through their ability to sense
pathogen-associated molecular patterns and products of tissue damage,. Transcriptional …
pathogen-associated molecular patterns and products of tissue damage,. Transcriptional …