Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines
EC Lopes, E Valls, ME Figueroa, A Mazur, FG Meng… - Cancer research, 2008 - AACR
Aberrant CpG methylation of tumor suppressor gene regulatory elements is associated with
transcriptional silencing and contributes to malignant transformation of different tissues. It is …
transcriptional silencing and contributes to malignant transformation of different tissues. It is …
Regulation of hematopoietic development by ZBTB transcription factors
T Maeda - International journal of hematology, 2016 - Springer
Hematopoietic development is governed by the coordinated expression of lineage-and
differentiation stage-specific genes. Transcription factors play major roles in this process and …
differentiation stage-specific genes. Transcription factors play major roles in this process and …
Transcription factor effector domains
S Frietze, PJ Farnham - A handbook of transcription factors, 2011 - Springer
The last decade has seen an incredible breakthrough in technologies that allow histones,
transcription factors (TFs), and RNA polymerases to be precisely mapped throughout the …
transcription factors (TFs), and RNA polymerases to be precisely mapped throughout the …
Transcriptional activities of retinoic acid receptors.
P Lefebvre, PJ Martin, S Flajollet, S Dedieu… - Vitamins and …, 2005 - europepmc.org
Vitamin A derivatives plays a crucial role in embryonic development, as demonstrated by the
teratogenic effect of either an excess or a deficiency in vitamin A. Retinoid effects extend …
teratogenic effect of either an excess or a deficiency in vitamin A. Retinoid effects extend …
The regulatory repertoire of PLZF and SALL4 in undifferentiated spermatogonia
DL Lovelace, Z Gao, K Mutoji, YC Song… - …, 2016 - journals.biologists.com
Spermatogonial stem cells (SSCs) maintain spermatogenesis throughout adulthood through
balanced self-renewal and differentiation, yet the regulatory logic of these fate decisions is …
balanced self-renewal and differentiation, yet the regulatory logic of these fate decisions is …
TGF-β1-induced epithelial–mesenchymal transition and acetylation of Smad2 and Smad3 are negatively regulated by EGCG in human A549 lung cancer cells
Transforming growth factor-β1, the key ligand of Smad-dependent signaling pathway, is
critical for epithelial–mesenchymal transition during embryo-morphogenesis, fibrotic …
critical for epithelial–mesenchymal transition during embryo-morphogenesis, fibrotic …
The role of methyl-binding proteins in chromatin organization and epigenome maintenance
A Fournier, N Sasai, M Nakao… - Briefings in functional …, 2012 - academic.oup.com
Methylated DNA can be specifically recognized by a set of proteins called methyl-CpG-
binding proteins (MBPs), which belong to three different structural families in mammals: the …
binding proteins (MBPs), which belong to three different structural families in mammals: the …
DNA methylation 40 years later: Its role in human health and disease
MI Scarano, M Strazzullo, MR Matarazzo… - Journal of cellular …, 2005 - Wiley Online Library
A long path, initiated more than 40 years ago, has led to a deeper understanding of the
complexity of gene regulation in eukaryotic genomes. In addition to genetic mechanisms, the …
complexity of gene regulation in eukaryotic genomes. In addition to genetic mechanisms, the …
TCFs and Wnt/β-catenin signaling: more than one way to throw the switch
KM Cadigan - Current topics in developmental biology, 2012 - Elsevier
Wnts are conserved, secreted signaling proteins that can influence cell behavior by
stabilizing β-catenin. Accumulated β-catenin enters the nucleus, where it physically …
stabilizing β-catenin. Accumulated β-catenin enters the nucleus, where it physically …
Reversible SUMOylation of TBL1-TBLR1 regulates β-catenin-mediated Wnt signaling
Dysregulation of Wnt signaling has been implicated in tumorigenesis. The role of Transducin
β-like proteins TBL1-TBLR1 in the promotion of Wnt/β-catenin-mediated oncogenesis has …
β-like proteins TBL1-TBLR1 in the promotion of Wnt/β-catenin-mediated oncogenesis has …