Hepatic accumulation of S-adenosylmethionine in hamsters with non-alcoholic fatty liver disease associated with metabolic syndrome under selenium and vitamin E …
J Maria del Bas, B Rodríguez, F Puiggròs… - Clinical …, 2019 - portlandpress.com
Progression of non-alcoholic fatty liver disease (NAFLD) in the context of metabolic
syndrome (MetS) is only partially explored due to the lack of preclinical models. In order to …
syndrome (MetS) is only partially explored due to the lack of preclinical models. In order to …
Dysregulated cytokine metabolism, altered hepatic methionine metabolism and proteasome dysfunction in alcoholic liver disease
C McClain, S Barve, S Joshi‐Barve… - Alcoholism: Clinical …, 2005 - Wiley Online Library
Alcoholic liver disease (ALD) remains an important complication and cause of morbidity and
mortality from alcohol abuse. Major developments in our understanding of the mechanisms …
mortality from alcohol abuse. Major developments in our understanding of the mechanisms …
Expression of Wilms' tumor suppressor in the liver with cirrhosis: relation to hepatocyte nuclear factor 4 and hepatocellular function
C Berasain, JI Herrero, ER Garcıa-Trevijano, MA Avila… - Hepatology, 2003 - Elsevier
The Wilms' tumor suppressor WT1 is a transcriptional regulator present in the fetal but not in
the mature liver. Its expression and functional role in liver diseases remains unexplored. In …
the mature liver. Its expression and functional role in liver diseases remains unexplored. In …
[PDF][PDF] Hepatocyte growth factor induces MAT2A expression and histone acetylation in rat hepatocytes: role in liver regeneration
MU Latasa, A Boukaba, ER García-Trevijano… - FASEB …, 2001 - researchgate.net
Methionine adenosyltransferase (MAT) catalyzes the synthesis of S-adenosylmethionine
(AdoMet). MAT is the product of two genes: MAT1A and MAT2A. MAT1A is expressed in …
(AdoMet). MAT is the product of two genes: MAT1A and MAT2A. MAT1A is expressed in …
Analysis of liver proteome and identification of critical proteins affecting milk fat, protein, and lactose metabolism in dariy cattle with Itraq
L Xu, L Shi, L Liu, R Liang, Q Li, J Li, B Han… - Proteomics, 2019 - Wiley Online Library
In this study, the proteomes of liver tissues are investigated in three periods of the lactation
cycle of Holstein cows by using isobaric tag for relative and absolute quantification (iTRAQ) …
cycle of Holstein cows by using isobaric tag for relative and absolute quantification (iTRAQ) …
Unique adaptations in neonatal hepatic transcriptome, nutrient signaling, and one-carbon metabolism in response to feeding ethyl cellulose rumen-protected …
V Palombo, A Alharthi, F Batistel, C Parys, J Guyader… - BMC genomics, 2021 - Springer
Abstract Background Methionine (Met) supply during late-pregnancy enhances fetal
development in utero and leads to greater rates of growth during the neonatal period. Due to …
development in utero and leads to greater rates of growth during the neonatal period. Due to …
S-Adenosylmethionine revisited: its essential role in the regulation of liver function
MA Avila, ER Garcı́a-Trevijano, ML Martı́nez-Chantar… - Alcohol, 2002 - Elsevier
Dietary methionine is mainly metabolized in the liver where it is converted into S-
adenosylmethionine (AdoMet), the main biologic methyl donor. This reaction is catalyzed by …
adenosylmethionine (AdoMet), the main biologic methyl donor. This reaction is catalyzed by …
[HTML][HTML] Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice
K Ko, H Yang, M Noureddin, A Iglesia-Ara, M Xia… - Laboratory …, 2008 - Elsevier
Endotoxemia participates in the pathogenesis of many liver injuries. Lipopolysaccharide
(LPS) was shown to inactivate hepatic methionine adenosyltransferase (MAT), the enzyme …
(LPS) was shown to inactivate hepatic methionine adenosyltransferase (MAT), the enzyme …
MAT2A promotes porcine adipogenesis by mediating H3K27me3 at Wnt10b locus and repressing Wnt/β-catenin signaling
C Zhao, H Wu, N Qimuge, W Pang, X Li, G Chu… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Methionine adenosyltransferase (MAT) is a critical biological enzyme and that can catalyze
L-met and ATP to form S-adenosylmethionine (SAM), which is acted as a biological methyl …
L-met and ATP to form S-adenosylmethionine (SAM), which is acted as a biological methyl …
[HTML][HTML] S-Adenosylmethionine Negatively Regulates the Mitochondrial Respiratory Chain Repressor MCJ in the Liver
L Barbier-Torres, J Chhimwal, SY Kim… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Abstract MCJ (Methylation-Controlled J protein), an endogenous repressor of the
mitochondrial respiratory chain, is upregulated in multiple liver diseases but little is known …
mitochondrial respiratory chain, is upregulated in multiple liver diseases but little is known …