Association between early adverse life events and irritable bowel syndrome
BACKGROUND & AIMS: Although childhood and adult abuse are more prevalent among
patients with irritable bowel syndrome (IBS) than healthy individuals (controls), other types of …
patients with irritable bowel syndrome (IBS) than healthy individuals (controls), other types of …
The role of stress on physiologic responses and clinical symptoms in irritable bowel syndrome
L Chang - Gastroenterology, 2011 - gastrojournal.org
Stressors can be acute or chronic and range from daily hassles to life-threatening situations,
such as natural disasters and violence that trigger the “fight or flight” response. Over time …
such as natural disasters and violence that trigger the “fight or flight” response. Over time …
Creatine metabolism and psychiatric disorders: Does creatine supplementation have therapeutic value?
PJ Allen - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Athletes, body builders, and military personnel use dietary creatine as an ergogenic aid to
boost physical performance in sports involving short bursts of high-intensity muscle activity …
boost physical performance in sports involving short bursts of high-intensity muscle activity …
The epigenetics of social adversity in early life: implications for mental health outcomes
PO McGowan, M Szyf - Neurobiology of disease, 2010 - Elsevier
An organism's behavioral and physiological and social milieu influence and are influenced
by the epigenome, which is composed predominantly of chromatin and the covalent …
by the epigenome, which is composed predominantly of chromatin and the covalent …
Behavior genetics and postgenomics
E Charney - Behavioral and brain sciences, 2012 - cambridge.org
The science of genetics is undergoing a paradigm shift. Recent discoveries, including the
activity of retrotransposons, the extent of copy number variations, somatic and chromosomal …
activity of retrotransposons, the extent of copy number variations, somatic and chromosomal …
Perinatal high fat diet alters glucocorticoid signaling and anxiety behavior in adulthood
Maternal obesity carries significant health risks for offspring that manifest later in life,
including metabolic syndrome, cardiovascular disease and affective disorders …
including metabolic syndrome, cardiovascular disease and affective disorders …
Sexual dimorphism in environmental epigenetic programming
A Gabory, L Attig, C Junien - Molecular and cellular endocrinology, 2009 - Elsevier
The phenotype of an individual is the result of complex interactions between genotype and
current, past and ancestral environment leading to a lifelong remodelling of our …
current, past and ancestral environment leading to a lifelong remodelling of our …
Multigenerational and transgenerational inheritance of drug exposure: the effects of alcohol, opiates, cocaine, marijuana, and nicotine
NL Yohn, MS Bartolomei, JA Blendy - Progress in biophysics and molecular …, 2015 - Elsevier
Familial inheritance of drug abuse is composed of both genetic and environmental factors.
Additionally, epigenetic transgenerational inheritance may provide a means by which …
Additionally, epigenetic transgenerational inheritance may provide a means by which …
Butyrate histone deacetylase inhibitors
K Steliou, MS Boosalis, SP Perrine… - BioResearch open …, 2012 - liebertpub.com
In addition to being a part of the metabolic fatty acid fuel cycle, butyrate is also capable of
inducing growth arrest in a variety of normal cell types and senescence-like phenotypes in …
inducing growth arrest in a variety of normal cell types and senescence-like phenotypes in …
Predictive validity and early predictors of peer-victimization trajectories in preschool
Context From the time of school entry, chronic levels of victimization by one's peers predict a
multitude of psychiatric and physical health problems. However, developmental trajectories …
multitude of psychiatric and physical health problems. However, developmental trajectories …