Association between early adverse life events and irritable bowel syndrome

K Bradford, W Shih, EJ Videlock, AP Presson… - Clinical …, 2012 - Elsevier
BACKGROUND & AIMS: Although childhood and adult abuse are more prevalent among
patients with irritable bowel syndrome (IBS) than healthy individuals (controls), other types of …

The role of stress on physiologic responses and clinical symptoms in irritable bowel syndrome

L Chang - Gastroenterology, 2011 - gastrojournal.org
Stressors can be acute or chronic and range from daily hassles to life-threatening situations,
such as natural disasters and violence that trigger the “fight or flight” response. Over time …

Creatine metabolism and psychiatric disorders: Does creatine supplementation have therapeutic value?

PJ Allen - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Athletes, body builders, and military personnel use dietary creatine as an ergogenic aid to
boost physical performance in sports involving short bursts of high-intensity muscle activity …

The epigenetics of social adversity in early life: implications for mental health outcomes

PO McGowan, M Szyf - Neurobiology of disease, 2010 - Elsevier
An organism's behavioral and physiological and social milieu influence and are influenced
by the epigenome, which is composed predominantly of chromatin and the covalent …

Behavior genetics and postgenomics

E Charney - Behavioral and brain sciences, 2012 - cambridge.org
The science of genetics is undergoing a paradigm shift. Recent discoveries, including the
activity of retrotransposons, the extent of copy number variations, somatic and chromosomal …

Perinatal high fat diet alters glucocorticoid signaling and anxiety behavior in adulthood

A Sasaki, WC De Vega, S St-Cyr, P Pan, PO McGowan - Neuroscience, 2013 - Elsevier
Maternal obesity carries significant health risks for offspring that manifest later in life,
including metabolic syndrome, cardiovascular disease and affective disorders …

Sexual dimorphism in environmental epigenetic programming

A Gabory, L Attig, C Junien - Molecular and cellular endocrinology, 2009 - Elsevier
The phenotype of an individual is the result of complex interactions between genotype and
current, past and ancestral environment leading to a lifelong remodelling of our …

Multigenerational and transgenerational inheritance of drug exposure: the effects of alcohol, opiates, cocaine, marijuana, and nicotine

NL Yohn, MS Bartolomei, JA Blendy - Progress in biophysics and molecular …, 2015 - Elsevier
Familial inheritance of drug abuse is composed of both genetic and environmental factors.
Additionally, epigenetic transgenerational inheritance may provide a means by which …

Butyrate histone deacetylase inhibitors

K Steliou, MS Boosalis, SP Perrine… - BioResearch open …, 2012 - liebertpub.com
In addition to being a part of the metabolic fatty acid fuel cycle, butyrate is also capable of
inducing growth arrest in a variety of normal cell types and senescence-like phenotypes in …

Predictive validity and early predictors of peer-victimization trajectories in preschool

ED Barker, M Boivin, M Brendgen… - Archives of general …, 2008 - jamanetwork.com
Context From the time of school entry, chronic levels of victimization by one's peers predict a
multitude of psychiatric and physical health problems. However, developmental trajectories …