Epigenetic changes in the hypothalamic proopiomelanocortin and glucocorticoid receptor genes in the ovine fetus after periconceptional undernutrition

A Stevens, G Begum, A Cook, K Connor… - …, 2010 - academic.oup.com
Maternal food restriction is associated with the development of obesity in offspring. This
study examined how maternal undernutrition in sheep affects the fetal hypothalamic …

[HTML][HTML] Eating disorders during gestation: implications for mother's health, fetal outcomes, and epigenetic changes

G Sebastiani, V Andreu-Fernández… - Frontiers in …, 2020 - frontiersin.org
Introduction: Eating disorders (EDs) have increased globally in women of childbearing age,
related to the concern for body shape promoted in industrialized countries. Pregnancy may …

The canary in the coalmine: The sensitivity of mesolimbic dopamine to environmental adversity during development

LM Gatzke-Kopp - Neuroscience & Biobehavioral Reviews, 2011 - Elsevier
The hypothalamic–pituitary–adrenal axis has been the focus of extensive research with
regard to the phenotypic plasticity this system shows in response to environmental …

Methylation matters in child development: Toward developmental behavioral epigenetics

MH van IJzendoorn… - Child Development …, 2011 - Wiley Online Library
Child development might be conceptualized as experiences becoming sculpted in the
organism's DNA through methylation, one of the major epigenetic mechanisms of change …

Early‐life stress‐induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition

RD Moloney, RM Stilling, TG Dinan… - Neurogastroenterology …, 2015 - Wiley Online Library
Stressful life events, especially in childhood, can have detrimental effects on health and are
associated with a host of psychiatric and gastrointestinal disorders including irritable bowel …

Role of DNA methylation and the DNA methyltransferases in learning and memory

MJ Morris, LM Monteggia - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
Dynamic regulation of chromatin structure in postmitotic neurons plays an important role in
learning and memory. Methylation of cytosine nucleotides has historically been considered …

Environmental signals and transgenerational epigenetics

MK Skinner, C Guerrero-Bosagna - Epigenomics, 2009 - Future Medicine
The ability of an environmental factor or toxicant to promote a phenotype or disease state not
only in the individual exposed, but also in subsequent progeny for multiple generations, is …

[HTML][HTML] Epigenetics in personality disorders: today's insights

DM Gescher, KG Kahl, T Hillemacher, H Frieling… - Frontiers in …, 2018 - frontiersin.org
Objective: Epigenetic mechanisms have been described in several mental disorders, such
as mood disorders, anxiety disorders and schizophrenia. However, less is known about the …

Diversity and representation: Key issues for psychophysiological science

LM Gatzke‐Kopp - Psychophysiology, 2016 - Wiley Online Library
Abstract This Special Issue is devoted to the illustration and discussion of three key
demographic variables (sex/gender, race/ethnicity, and socioeconomic status) that have …

DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models

A Fuso, V Nicolia, RA Cavallaro, S Scarpa - The Journal of nutritional …, 2011 - Elsevier
Late-onset Alzheimer's disease seems to be a multi-factorial disease with both genetic and
non-genetic, environmental, possible causes. Recently, epigenomics is achieving a major …