Epigenetic alterations and prenatal maternal depression
Major depressive disorder of the mother affects 6 to 17% of pregnancies worldwide and can
lead to negative outcomes, such as preterm delivery and later mental health problems of the …
lead to negative outcomes, such as preterm delivery and later mental health problems of the …
The contribution of genetic and environmental factors to the duration of pregnancy
TP York, LJ Eaves, MC Neale, JF Strauss III - American Journal of …, 2014 - Elsevier
This review describes how improvements in biometric-genetic studies of twin kinships, half-
sibships, and cousinships have now demonstrated a sizeable fetal genetic and maternal …
sibships, and cousinships have now demonstrated a sizeable fetal genetic and maternal …
MBD-seq as a cost-effective approach for methylome-wide association studies: demonstration in 1500 case–control samples
Aim: We studied the use of methyl-CpG binding domain (MBD) protein-enriched genome
sequencing (MBD-seq) as a cost-effective screening tool for methylome-wide association …
sequencing (MBD-seq) as a cost-effective screening tool for methylome-wide association …
Testing two models describing how methylome-wide studies in blood are informative for psychiatric conditions
Aim: As the primary relevant tissue (brain) for psychiatric disorders is commonly not
available, we aimed to investigate whether blood can be used as a proxy in methylation …
available, we aimed to investigate whether blood can be used as a proxy in methylation …
[HTML][HTML] Examining the biological mechanisms of human mental disorders resulting from gene-environment interdependence using novel functional genomic …
PP Silveira, MJ Meaney - Neurobiology of Disease, 2023 - Elsevier
We explore how functional genomics approaches that integrate datasets from human and
non-human model systems can improve our understanding of the effect of gene …
non-human model systems can improve our understanding of the effect of gene …
In utero life and epigenetic predisposition for disease
KL Thornburg, J Shannon, P Thuillier, MS Turker - Advances in genetics, 2010 - Elsevier
Regulatory regions of the human genome can be modified through epigenetic processes
during prenatal life to make an individual more likely to suffer chronic diseases when they …
during prenatal life to make an individual more likely to suffer chronic diseases when they …
The epigenetics of suicide: explaining the biological effects of early life environmental adversity
A number of recent studies have shown epigenetic alterations associated with suicidal
behavior. These epigenetic mechanisms, which alter gene expression via alternative …
behavior. These epigenetic mechanisms, which alter gene expression via alternative …
Cross-fostering: elucidating the effects of gene× environment interactions on phenotypic development
R McCarty - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Cross-fostering of litters from soon after birth until weaning is a valuable tool to study the
ways in which gene× environment interactions program the development of neural …
ways in which gene× environment interactions program the development of neural …
The effects of maternal and postnatal dietary methyl nutrients on epigenetic changes that lead to non-communicable diseases in adulthood
RS Randunu, RF Bertolo - International journal of molecular sciences, 2020 - mdpi.com
The risk for non-communicable diseases in adulthood can be programmed by early nutrition.
This programming is mediated by changes in expression of key genes in various metabolic …
This programming is mediated by changes in expression of key genes in various metabolic …
Genomic features of the human dopamine transporter gene and its potential epigenetic states: implications for phenotypic diversity
E Shumay, JS Fowler, ND Volkow - PloS one, 2010 - journals.plos.org
Human dopamine transporter gene (DAT1 or SLC6A3) has been associated with various
brain-related diseases and behavioral traits and, as such, has been investigated intensely in …
brain-related diseases and behavioral traits and, as such, has been investigated intensely in …