Bulk sequencing methodologies have allowed us to make great progress in cancer
research. Unfortunately, these techniques lack the resolution to fully unravel the epigenetic …

The holobiont concept (ie, multiple living beings in close symbiosis with one another and
functioning as a unit) is revolutionizing our understanding of biology, especially in marine …

Crop production is the primary goal of agricultural activities, which is always taken into
consideration. However, global agricultural systems are coming under increasing pressure …

Urine markers to detect bladder cancer have been the subject of research for decades. The
idea that urine—being in continuous contact with tumour tissue—should provide a vector of …

Epigenetic modifications are defined as heritable changes in gene activity that do not
involve changes in the underlying DNA sequence. The oncogenic process is driven by the …

The OMICs cascade describes the hierarchical flow of information through biological
systems. The epigenome sits at the apex of the cascade, thereby regulating the RNA and …

Despite advancements in treatment protocols, cancer is one of the leading cause of deaths
worldwide. Therefore, there is a need to identify newer and personalized therapeutic targets …

Genetic information is not transmitted solely by DNA but by the epigenetics process.
Epigenetics describes molecular missing link pathways that could bridge the gap between …

Multiple strategies are continuously being explored to expand the drug target repertoire in
solid tumors. We devised a novel computational workflow for transcriptome‐wide gene …

In the setting of chronic antigen exposure in the tumor microenvironment (TME), cytotoxic
CD8+ T cells (CTLs) lose their immune surveillance capabilities and ability to clear tumor …