Roles of long non-coding RNAs in the development of aging-related neurodegenerative diseases
YQ Ni, H Xu, YS Liu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Aging-related neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's
disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are …
disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are …
LncRNA H19 promotes tumor angiogenesis in smokers by targeting anti-angiogenic miRNAs
M Shirvaliloo - Epigenomics, 2023 - Taylor & Francis
A key concept in drug discovery is the identification of candidate therapeutic targets such as
long noncoding RNAs (lncRNAs) because of their extensive involvement in neoplasms, and …
long noncoding RNAs (lncRNAs) because of their extensive involvement in neoplasms, and …
The long non‐coding RNA LINDA restrains cellular collapse following DNA damage in Arabidopsis thaliana
J Herbst, SH Nagy, I Vercauteren… - The Plant …, 2023 - Wiley Online Library
The genomic integrity of every organism is endangered by various intrinsic and extrinsic
stresses. To maintain genomic integrity, a sophisticated DNA damage response (DDR) …
stresses. To maintain genomic integrity, a sophisticated DNA damage response (DDR) …
A cuproptosis-related lncRNAs signature for prognosis, chemotherapy, and immune checkpoint blockade therapy of low-grade glioma
X Yan, N Wang, J Dong, F Wang, J Zhang… - Frontiers in Molecular …, 2022 - frontiersin.org
Cuproptosis is a new type of cell death that is associated with mitochondrial respiration of
the tricarboxylic acid cycle. Previous studies showed that long non-coding RNAs (lncRNAs) …
the tricarboxylic acid cycle. Previous studies showed that long non-coding RNAs (lncRNAs) …
Exploration of the Noncoding Genome for Human-Specific Therapeutic Targets—Recent Insights at Molecular and Cellular Level
W Poller, S Sahoo, R Hajjar, U Landmesser… - Cells, 2023 - mdpi.com
While it is well known that 98–99% of the human genome does not encode proteins, but are
nevertheless transcriptionally active and give rise to a broad spectrum of noncoding RNAs …
nevertheless transcriptionally active and give rise to a broad spectrum of noncoding RNAs …
Effects of HAR1 on cognitive function in mice and the regulatory network of HAR1 determined by RNA sequencing and applied bioinformatics analysis
L Zhang, S Lin, K Huang, A Chen, N Li, S Shen… - Frontiers in …, 2023 - frontiersin.org
Background: HAR1 is a 118-bp segment that lies in a pair of novel non-coding RNA genes. It
shows a dramatic accelerated change with an estimated 18 substitutions in the human …
shows a dramatic accelerated change with an estimated 18 substitutions in the human …
The expression profile of HAR1A and HAR1B in the peripheral blood cells of multiple sclerosis patients
S Akbarzadeh, S Tayefeh-Gholami, P Najari… - Molecular Biology …, 2023 - Springer
Background Multiple sclerosis (MS) is a progressive neurodegenerative disease of the
central nervous system (CNS) with varying degrees of axonal and neuronal damage. The …
central nervous system (CNS) with varying degrees of axonal and neuronal damage. The …
Combining multi-omics approaches to prioritize the variant-regulated functional long non-coding RNAs in autism spectrum disorder
H Wang, X Wu, Y Chen, F Hou, K Zhu, Q Jiang… - Asian Journal of …, 2023 - Elsevier
Objective Rising evidence has indicated that long non-coding RNA (lncRNA) may play an
essential role in the development of autism spectrum disorder (ASD). However, identifying …
essential role in the development of autism spectrum disorder (ASD). However, identifying …
Long non-coding RNAs with essential roles in neurodegenerative disorders
W Xiong, L Lu, J Li - Neural Regeneration Research, 2024 - journals.lww.com
Recently, with the advent of high-resolution and high-throughput sequencing technologies,
an increasing number of long non-coding RNAs (lncRNAs) have been found to be involved …
an increasing number of long non-coding RNAs (lncRNAs) have been found to be involved …
长链非编码RNA 在神经退行性疾病中的重要作用
W Xiong, L Lu, J Li - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
近年来, 随着高分辨率和高通量测序技术的出现, 越来越多的长链非编码RNA
被发现以特定的时空模式参与中枢神经系统神经元功能的调节, 甚至也参与不同神经退行性疾病 …
被发现以特定的时空模式参与中枢神经系统神经元功能的调节, 甚至也参与不同神经退行性疾病 …