Diabetic Retinopathy (DR) is one of the most important microvascular complications of
diabetes mellitus, which can lead to blindness in severe cases. Mitochondria are energy …

Impaired insulin secretion from pancreatic islets is a hallmark of type 2 diabetes (T2D).
Altered chromatin structure may contribute to the disease. We therefore studied the impact of …

Elderly patients often suffer from multiple age-related diseases. Here we show that the
expression of DJ-1, an antioxidant protein with reduced expression in the central nervous …

To elucidate the mechanisms related to the development of type 2 diabetes (T2D) and other
degenerative diseases at a molecular level, a better understanding of the changes in the …

Diabetes is a severe threat to global health. Almost 500 million people live with diabetes
worldwide. Most of them have type 2 diabetes (T2D). T2D patients are at risk of developing …

The effectiveness of herbal medicine in treating diabetes has grown in recent years, but the
precise mechanism by which it does so is still unclear to both medical professionals and …

Metabolic diseases and their complications impose health and economic burdens
worldwide. Evidence from past experimental studies and clinical trials suggests our body …

Several recent reports have described associations between gestational diabetes (GDM)
and changes to the epigenomic landscape where the DNA samples were derived from …

Aims/hypothesis Pancreatic beta cell dysfunction is a prerequisite for the development of
type 2 diabetes. Histone deacetylases (HDACs) may affect pancreatic endocrine function …

Individuals with type 2 diabetes (T2D) display vascular insulin resistance and decreased
nitric oxide production leading to vasoconstriction and atherosclerosis. Soluble factors such …