Dynamics of epigenetic modifications in ICSI embryos from in vitro‐produced spermatozoa
A Oblette, A Rives‐Feraille, L Dumont, M Delessard… - …, 2021 - Wiley Online Library
Background In prepubertal boys with cancer, fertility preservation relies on testicular tissue
freezing before treatment. In vitro maturation of frozen/thawed tissues could be one of the …
freezing before treatment. In vitro maturation of frozen/thawed tissues could be one of the …
Demethylation of non-CpG sites in DNA is initiated by TET2 5-methylcytosine dioxygenase
In the mammalian genome, cytosine methylation predominantly occurs at CpG sites. In
addition, a number of recent studies have uncovered extensive C5 cytosine methylation …
addition, a number of recent studies have uncovered extensive C5 cytosine methylation …
Alterations in oocytes and early zygotes following oral exposure to di (2-ethylhexyl) phthalate in young adult female mice
LY Parra-Forero, A Veloz-Contreras… - Reproductive …, 2019 - Elsevier
Abstract Because di (2-ethylhexyl) phthalate (DEHP) toxicity on ovarian function is
incomplete, effects of DEHP oocyte fertilization and the resulting zygotes were investigated …
incomplete, effects of DEHP oocyte fertilization and the resulting zygotes were investigated …
Epigenetics Mechanism and Therapeutic Potential of Approved Epi-drugs in Pulmonary Hypertension Disease
L Zhanqiang, H Huoqiang… - Current Topics in …, 2023 - ingentaconnect.com
Epigenetics is defined as a heritable change occurring in gene expression and phenotype
without altering the underlying primary DNA sequence itself. Epigenetic variation consists of …
without altering the underlying primary DNA sequence itself. Epigenetic variation consists of …
TET3 dioxygenase modulates gene conversion at the avian immunoglobulin variable region via demethylation of non‐CpG sites in pseudogene templates
N Takamura, H Seo, K Ohta - Genes to Cells, 2021 - Wiley Online Library
Diversification of the avian primary immunoglobulin (Ig) repertoire is achieved in developing
B cells by somatic hypermutation (SHM) and gene conversion (GCV). GCV is a type of …
B cells by somatic hypermutation (SHM) and gene conversion (GCV). GCV is a type of …
Fetal origins of obesity: a novel pathway of regulating appetite neurons in the hypothalamus of growth-restricted rat offspring
W Han, Z Song, D Shan, Q Shi - Archives of Gynecology and Obstetrics, 2023 - Springer
Purpose Fetal growth restriction causes a series of sequelae, some of which, such as
hyperphagia, reduced satiety and postnatal obesity, are believed to be associated with …
hyperphagia, reduced satiety and postnatal obesity, are believed to be associated with …
[图书][B] Metabolomics and Chemical Library Screening for Antibacterial Drug Discovery
NJ Ayon - 2020 - search.proquest.com
There are twenty standard amino acids which are proteinogenic and can exist in two
stereoisomeric forms, D-and L-enantiomers, except for glycine, which is achiral. The D …
stereoisomeric forms, D-and L-enantiomers, except for glycine, which is achiral. The D …
Synthesis of NSC 106084 and NSC 14778 and evaluation of their DNMT inhibitory activity
M Leroy, L Mélin, SR LaPlante… - Bioorganic & Medicinal …, 2019 - Elsevier
DNA methylation is an epigenetic modification that is performed by DNA methyltransferases
(DNMTs) and that leads to the transfer of a methyl group from S-adenosylmethionine (SAM) …
(DNMTs) and that leads to the transfer of a methyl group from S-adenosylmethionine (SAM) …
[图书][B] Characterization of 5-Methylcytosine Dioxygenase TET2 and Rescue of Mutant TET2 Activity by Using Turbo Co-Substrate
C Bhattacharya - 2023 - search.proquest.com
Regulation of epigenetic transcription mediated by 5-methylcytosine (5mC) plays a critical
role in eukaryotic development. Demethylation of these epigenetic marks is accomplished …
role in eukaryotic development. Demethylation of these epigenetic marks is accomplished …