Statins reduce abdominal aortic aneurysm growth, rupture, and perioperative mortality: a systematic review and meta‐analysis
K Salata, M Syed, MA Hussain… - Journal of the …, 2018 - Am Heart Assoc
Background There are no recognized pharmacological treatments for abdominal aortic
aneurysms (AAA), although statins are suggested to be beneficial. We sought to summarize …
aneurysms (AAA), although statins are suggested to be beneficial. We sought to summarize …
[HTML][HTML] The abdominal aortic aneurysm and intraluminal thrombus: current concepts of development and treatment
A Piechota-Polanczyk, A Jozkowicz… - Frontiers in …, 2015 - frontiersin.org
The pathogenesis of the abdominal aortic aneurysm (AAA) shows several hallmarks of
atherosclerotic and atherothrombotic disease, but comprises an additional, predominant …
atherosclerotic and atherothrombotic disease, but comprises an additional, predominant …
Ruptured abdominal aortic aneurysm—epidemiology, predisposing factors, and biology
T Schmitz-Rixen, M Keese, M Hakimi, A Peters… - … archives of surgery, 2016 - Springer
Purpose Abdominal aortic aneurysm is a common degenerative vascular disorder
associated with sudden death due to aortic rupture. This review describes epidemiology …
associated with sudden death due to aortic rupture. This review describes epidemiology …
[HTML][HTML] A systematic review and meta-analysis of sex-and gender-based differences in presentation severity and outcomes in adults undergoing major vascular …
Background Studies have investigated the effects of gender on vascular surgery care.
However, to the best of our knowledge, no comprehensive synthesis of the literature has …
However, to the best of our knowledge, no comprehensive synthesis of the literature has …
Genetic ablation of microRNA-33 attenuates inflammation and abdominal aortic aneurysm formation via several anti-inflammatory pathways
Objective—Abdominal aortic aneurysm (AAA) is an increasingly prevalent and ultimately
fatal disease with no effective pharmacological treatment. Because matrix degradation …
fatal disease with no effective pharmacological treatment. Because matrix degradation …
The role of endothelial dysfunction in aortic aneurysms
G Siasos, K Mourouzis, E Oikonomou… - Current …, 2015 - ingentaconnect.com
Abdominal aortic aneurysm is a vascular disease which, despite the fact that it shares
common risk factors with atherosclerosis, develops in parallel but as a partly independent …
common risk factors with atherosclerosis, develops in parallel but as a partly independent …
A quarter of a century biomechanical rupture risk assessment of abdominal aortic aneurysms. Achievements, clinical relevance, and ongoing developments
Abdominal aortic aneurysm (AAA) disease, the local enlargement of the infrarenal aorta, is a
serious condition that causes many deaths, especially in men exceeding 65 years of age …
serious condition that causes many deaths, especially in men exceeding 65 years of age …
Pharmacotherapy in clinical trials for abdominal aortic aneurysms: A systematic review and meta-analysis
Z Su, J Guo, Y Gu - Clinical and Applied Thrombosis …, 2022 - journals.sagepub.com
Objective There is no medical treatment proven to limit abdominal aortic aneurysm (AAA)
progression. This systematic review aimed to summarise available trial evidence on the …
progression. This systematic review aimed to summarise available trial evidence on the …
[HTML][HTML] Inhibition of endoplasmic reticulum stress signaling pathway: a new mechanism of statins to suppress the development of abdominal aortic aneurysm
Y Li, G Lu, D Sun, H Zuo, DW Wang, J Yan - PloS one, 2017 - journals.plos.org
Background Abdominal aortic aneurysm (AAA) is a potentially lethal disease with extremely
poor survival rates once the aneurysm ruptures. Statins may exert beneficial effects on the …
poor survival rates once the aneurysm ruptures. Statins may exert beneficial effects on the …
[HTML][HTML] Adventitial adipogenic degeneration is an unidentified contributor to aortic wall weakening in the abdominal aortic aneurysm
SA Doderer, G Gäbel, VBC Kokje, BH Northoff… - Journal of Vascular …, 2018 - Elsevier
Objective The processes driving human abdominal aortic aneurysm (AAA) progression are
not fully understood. Although antiinflammatory and proteolytic strategies effectively quench …
not fully understood. Although antiinflammatory and proteolytic strategies effectively quench …