Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is a central method in
epigenomic research. Genome-wide analysis of histone modifications, such as enhancer …

Growing evidence shows that epigenetic mechanisms contribute to complex traits, with
implications across many fields of biology. In plant ecology, recent studies have attempted to …

Abstract The Cistrome Data Browser (DB) is a resource of human and mouse cis-regulatory
information derived from ChIP-seq, DNase-seq and ATAC-seq chromatin profiling assays …

Recent developments in stem cell biology have enabled the study of cell fate decisions in
early human development that are impossible to study in vivo. However, understanding how …

Summary S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) link one-
carbon metabolism to methylation status. However, it is unknown whether regulation of SAM …

Plant genomes encode a complex and evolutionary diverse regulatory grammar that forms
the basis for most life on earth. A wealth of regulome and epigenome data have been …

Due to the ability to regulate target metabolic pathways globally and dynamically, metabolic
regulation systems composed of transcription factors have been widely used in metabolic …

Intron retention (IR) is a form of alternative splicing that has long been neglected in
mammalian systems although it has been studied for decades in non-mammalian species …

With the advent of ChIP-seq multiplexing technologies and the subsequent increase in ChIP-
seq throughput, the development of working standards for the quality assessment of ChIP …

MEME-ChIP is a web-based tool for analyzing motifs in large DNA or RNA data sets. It can
analyze peak regions identified by ChIP-seq, cross-linking sites identified by CLIP-seq and …