Cryopreservation of biological materials such as cells, tissues, and organs is a prevailing
topic of high importance. It is employed not only in many research fields but also in the …

Post-stroke cognitive impairment (PSCI), commonly seen in the clinical practice, is a major
factor impeding patient rehabilitation. Enriched environment (EE) intervention is a simple …

Microglial dysfunction and inflammation have recently been shown to be related to the
development of Alzheimer's disease (AD). Inositol polyphosphate-5-phosphatase (INPP5D) …

Adult-onset neurological disorders are caused and influenced by a multitude of different
factors, including epigenetic modifications. Here, using an ELISA kit selected upon careful …

Background and purpose The prevalence of cerebral small vessel disease (CSVD) is
increasing due to the accelerating global aging process, resulting in a substantial burden on …

Epigenetic mechanisms such as DNA methylation have been implicated in a number of
diseases including cancer, heart disease, autoimmune disorders, and neurodegenerative …

DNA methylation changes play essential roles in regulating the activities of genes involved
in immune responses. Understanding of variable DNA methylation linked to immune …

Mesial temporal lobe epilepsy (MTLE) is a common epileptic disorder; little is known
whether it is associated with peripheral epigenetic changes. Here we compared blood …

Abstract Background Neurodegeneration in Alzheimer's disease can be caused by
accumulation of oxidative DNA damage resulting from altered expression of genes involved …

Epigenetic mechanisms play an important role in the development and progression of
various neurodegenerative diseases. Abnormal methylation of numerous genes responsible …