Late-onset Alzheimer disease (LOAD) is the most frequent cause of dementia in elderly
adults. However, the factors determining disease onset remain unclear. In the elderly, the …

Background The quantification of global DNA methylation has been established in
epigenetic screening. As more practicable alternatives to the HPLC-based gold standard …

Late-onset sporadic Alzheimer's disease (LOAD) seems to contain a “hidden” component
that cannot be explained by classical Mendelian genetics, with advanced aging being the …

Background: Neurodegenerative disorders are one of the major health problems in Western
countries. Genetic and epigenetic mechanisms play crucial roles in the origin and …

As the European population gets older, the incidence of neurological disorders increases
with significant impact on social costs. Despite differences in disease etiology, several brain …

Working memory impairment is a common cognitive dysfunction after traumatic brain injury
(TBI), which severely affects the quality of life of patients. Acetylcholine is a neurotransmitter …

Deep learning (DL) is a rising field that is applied in forensic science and criminal
investigation (FSCI). FSCI specialists are confronting many difficulties because of the …

Tyrosine kinase inhibitors (TKIs), which have been developed and approved for cancer
treatment in the last few years, are involved in synaptic plasticity of learning and memory …

Human samples are commonly collected and long-term stored in biobanks for current and
future analyses. Even though techniques for freezing human blood are well established, the …

Mitochondrial (mt) DNA haplogroups, defined by specific single nucleotide polymorphism
(SNP) patterns, represent populations of diverse geographic origins and have been …