Background: The recent interest of clinical laboratories in developing serum testosterone
assays based on isotope dilution–liquid chromatography–tandem mass spectrometry (ID-LC …

BACKGROUND 25-hydroxyvitamin D [25 (OH) D] assays are characterized by poor between-
assay comparability. This result emphasizes the need for reference measurement …

The isotope dilution mass spectrometry (IDMS) technique is well known and widely reported
in the literature. However, its application can present considerable difficulties with regard to …

Uric acid is an important diagnostic marker of catabolism of the purine nucleosides, and
accurate measurements of serum uric acid are necessary for proper diagnosis of gout or …

The inaccuracy of routine serum 25-hydroxyvitamin D measurements hampers the
interpretation of data in patient care and public health research. We developed and …

BACKGROUND: Serum free thyroxine (FT4) testing in pregnancy is known to be challenging
for immunoassays (IAs). We verified the reliability of FT4 results by 3 commercial IAs …

A new candidate reference method is presented for the determination of thyroxine in serum.
The method is based on isotope dilution‐liquid chromatography/tandem mass spectrometry …

Abstract The IFCC Working Group for Standardization of Thyroid Function Tests proposes a
candidate international conventional reference procedure (RMP) for measurement of the …

At the level of the whole animal, the toxic effects of the mycotoxin deoxynivalenol (DON)
range from causing diarrhoea, vomiting, gastro-intestinal inflammation to necrosis of several …

Metrological Traceability is an essential task to support standardization and thereby the
performance of clinical chemical testing, finally for the benefit of the patients. The …