The societal opportunities and challenges of genome editing

D Carroll, RA Charo - Genome biology, 2015 - Springer
The genome editing platforms currently in use have revolutionized the field of genetics. At an
accelerating rate, these tools are entering areas with direct impact on human well being …

[HTML][HTML] Polygenic scores for ADHD: a meta-analysis

JJ Li, Q He - Research on Child and Adolescent Psychopathology, 2021 - Springer
Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental
disorder that is known to have a polygenic (ie, many genes of individually small effects) …

Discussions of the “not so fit”: how ableism limits diverse thought and investigative potential in evolutionary biology

HA Branch, AN Klingler, KJRP Byers… - The American …, 2022 - journals.uchicago.edu
Evolutionary biology and many of its foundational concepts are grounded in a history of
ableism and eugenics. The field has not made a concerted effort to divest our concepts and …

Toward a framework for assessing privacy risks in multi-omic research and databases

C Dupras, EM Bunnik - The American Journal of Bioethics, 2021 - Taylor & Francis
While the accumulation and increased circulation of genomic data have captured much
attention over the past decade, privacy risks raised by the diversification and integration of …

You can't keep a bad idea down: Dark history, death, and potential rebirth of eugenics

M Liscum, ML Garcia - The Anatomical Record, 2022 - Wiley Online Library
Abstract “Be careful what you wish for”: This adage guides both how this project came to life,
and how the topic covered in this review continues to unfold. What began as talks between …

The relationship between the genetic counseling profession and the disability community: a commentary

AC Madeo, BB Biesecker, C Brasington… - American journal of …, 2011 - Wiley Online Library
Since the inception of the field of genetic counseling, the profession has had a tenuous
relationship with the disability community. Genetic counselors both offer prenatal diagnostic …

Delayed diagnosis and racial bias in children with genetic conditions

J Omorodion, L Dowsett, RD Clark… - American Journal of …, 2022 - Wiley Online Library
As more therapeutics for genetic conditions become available, the need for timely and
equitable genetic diagnosis has become urgent. Using clinical cases, we consider the …

[HTML][HTML] Genetic counseling for prenatal testing: where is the discussion about disability?

E Farrelly, MK Cho, L Erby, D Roter, A Stenzel… - Journal of genetic …, 2012 - Springer
There are little data revealing how genetic counselors talk about disability in the prenatal
setting. We performed a qualitative analysis of 93 existing transcripts from simulated patient …

Looking into the shadow: the eugenics argument in debates on reproductive technologies and practices

G Cavaliere - Monash Bioethics Review, 2018 - Springer
Eugenics is often referred to in debates on the ethics of reproductive technologies and
practices, in relation to the creation of moral boundaries between acceptable and …

Down syndrome: coercion and eugenics

LL McCabe, ERB McCabe - Genetics in Medicine, 2011 - nature.com
Experts agree that coercion by insurance companies or governmental authorities to limit
reproductive choice constitutes a eugenic practice. We discuss discrimination against …