Linking environmental risk factors with epigenetic mechanisms in Parkinson's disease
M Tsalenchuk, SM Gentleman, SJ Marzi - npj Parkinson's Disease, 2023 - nature.com
Sporadic Parkinson's disease (PD) is a progressive neurodegenerative disease, with a
complex risk structure thought to be influenced by interactions between genetic variants and …
complex risk structure thought to be influenced by interactions between genetic variants and …
Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health
O Babenko, I Kovalchuk, GAS Metz - Neuroscience & Biobehavioral …, 2015 - Elsevier
Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …
stressful experiences during pregnancy exert long-term consequences on the future mental …
Promoter DNA hypermethylation and paradoxical gene activation
DNA methylation is a stable epigenetic modification that contributes to the spatiotemporal
regulation of gene expression. The manner in which DNA methylation contributes to …
regulation of gene expression. The manner in which DNA methylation contributes to …
Epigenetics and gene expression
ER Gibney, CM Nolan - Heredity, 2010 - nature.com
Transcription, translation and subsequent protein modification represent the transfer of
genetic information from the archival copy of DNA to the short-lived messenger RNA, usually …
genetic information from the archival copy of DNA to the short-lived messenger RNA, usually …
Transcriptional and epigenetic mechanisms of addiction
AJ Robison, EJ Nestler - Nature reviews neuroscience, 2011 - nature.com
Investigations of long-term changes in brain structure and function that accompany chronic
exposure to drugs of abuse suggest that alterations in gene regulation contribute …
exposure to drugs of abuse suggest that alterations in gene regulation contribute …
Nonviral gene delivery: principle, limitations, and recent progress
MS Al-Dosari, X Gao - The AAPS journal, 2009 - Springer
Gene therapy is becoming a promising therapeutic modality for the treatment of genetic and
acquired disorders. Nonviral approaches as alternative gene transfer vehicles to the popular …
acquired disorders. Nonviral approaches as alternative gene transfer vehicles to the popular …
Plant volatile organic compounds evolution: transcriptional regulation, epigenetics and polyploidy
Volatile organic compounds (VOCs) are emitted by plants as a consequence of their
interaction with biotic and abiotic factors, and have a very important role in plant evolution …
interaction with biotic and abiotic factors, and have a very important role in plant evolution …
High‐throughput sequencing for biology and medicine
WW Soon, M Hariharan, MP Snyder - Molecular systems biology, 2013 - embopress.org
Advances in genome sequencing have progressed at a rapid pace, with increased
throughput accompanied by plunging costs. But these advances go far beyond faster and …
throughput accompanied by plunging costs. But these advances go far beyond faster and …
Recent progress, methods and perspectives in forensic epigenetics
A Vidaki, M Kayser - Forensic Science International: Genetics, 2018 - Elsevier
Forensic epigenetics, ie, investigating epigenetics variation to resolve forensically relevant
questions unanswerable with standard forensic DNA profiling has been gaining substantial …
questions unanswerable with standard forensic DNA profiling has been gaining substantial …
Molecular mechanisms of gene silencing mediated by DNA methylation
M Curradi, A Izzo, G Badaracco… - Molecular and cellular …, 2002 - Am Soc Microbiol
DNA methylation and chromatin modification operate along a common pathway to repress
transcription; accordingly, several experiments demonstrate that the effects of DNA …
transcription; accordingly, several experiments demonstrate that the effects of DNA …