Vitamin D is not really a vitamin but the precursor to the potent steroid hormone calcitriol,
which has widespread actions throughout the body. Calcitriol regulates numerous cellular …

Although colorectal cancer (CRC) screening has reduced the incidence of and mortality from
CRC, chemoprevention strategies have the potential to further reduce CRC incidence and …

Importance Evidence suggests that low vitamin D status may increase the risk of cancer.
Objective To determine if dietary supplementation with vitamin D 3 and calcium reduces the …

Background Epidemiologic and preclinical data suggest that higher intake and serum levels
of vitamin D and higher intake of calcium reduce the risk of colorectal neoplasia. To further …

Vitamin D and its active metabolites are important nutrients for human skeletal health. UV
irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the …

The active form of vitamin D 3, 1, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3), is primarily
known as a key regulator of calcium and phosphate homeostasis. It exerts its biological …

Objetivo Apresentar uma atualização sobre o diagnóstico e tratamento da hipovitaminose D
baseada nas mais recentes evidências científicas. Materiais e métodos O Departamento de …

Oral cancer is known as one of the most common cancers, with a poor prognosis, related to
delayed clinical diagnosis, either due to the lack of particular biomarkers related to the …

Objective: The objective is to present an update on the diagnosis and treatment of
hypovitaminosis D, based on the most recent scientific evidence. Materials and methods …

The Wnt/β-catenin signaling pathway is abnormally activated in most colorectal cancers and
in a proportion of other neoplasias. This activation initiates or contributes to carcinogenesis …