[HTML][HTML] The influence of physiological and pathological perturbations on blood-brain barrier function

N Zhao, TD Chung, Z Guo, JJ Jamieson… - Frontiers in …, 2023 - frontiersin.org
The blood-brain barrier (BBB) is located at the interface between the vascular system and
the brain parenchyma, and is responsible for communication with systemic circulation and …

Blood-brain barrier changes in high altitude

JV Lafuente, G Bermudez… - CNS & Neurological …, 2016 - ingentaconnect.com
Cerebral syndromes related to high-altitude exposure are becoming more frequent as the
number of trips to high altitudes has increased in the last decade. The commonest symptom …

Minocycline ameliorates hypoxia-induced blood–brain barrier damage by inhibition of HIF-1α through SIRT-3/PHD-2 degradation pathway

F Yang, L Zhou, D Wang, Z Wang, QY Huang - Neuroscience, 2015 - Elsevier
Background: Minocycline, a second-generation tetracycline alleviates neuro-inflammation
and protects the blood–brain barrier (BBB) in ischemia stroke. However, the effect of …

Tetrahydrocurcumin mitigates acute hypobaric hypoxia‐induced cerebral oedema and inflammation through the NF‐κB/VEGF/MMP‐9 pathway

Y Pan, Y Zhang, J Yuan, X Ma, Y Zhao… - Phytotherapy …, 2020 - Wiley Online Library
High‐altitude cerebral oedema (HACE) is a potentially fatal manifestation of high‐altitude
sickness and is caused partly by inflammation and the blood–brain barrier disruption …

Roles of the hypoximir microRNA‐424/322 in acute hypoxia and hypoxia‐induced pulmonary vascular leakage

SH Tsai, PH Huang, HY Tsai, YJ Hsu… - The FASEB …, 2019 - Wiley Online Library
Acute mountain sickness (AMS) occurs in up to 25% of unacclimatized persons who ascend
to 3000 m and can result in high‐altitude pulmonary edema (HAPE). MicroRNAs (miRs) can …

Protective effect of 5, 6, 7, 8-Tetrahydroxyflavone on high altitude cerebral edema in rats

L Jing, N Wu, J Zhang, Q Da, H Ma - European Journal of Pharmacology, 2022 - Elsevier
High altitude cerebral edema (HACE) is a potentially life-threatening disease encountered at
high altitudes. However, effective methods for HACE prophylaxis are limited. Convincing …

Progress in the Treatment of High Altitude Cerebral Edema: Targeting REDOX Homeostasis

Y Li, C Li, T Luo, T Yue, W Xiao, L Yang… - Journal of …, 2023 - Taylor & Francis
With the increasing of altitude activities from low-altitude people, the study of high altitude
cerebral edema (HACE) has been revived. HACE is a severe acute mountain sickness …

Establishment of an experimental rat model of high altitude cerebral edema by hypobaric hypoxia combined with temperature fluctuation

L Jing, N Wu, L He, J Shao, H Ma - Brain Research Bulletin, 2020 - Elsevier
High altitude cerebral edema (HACE) is a kind of life threat disease encountered at high
altitude, but the precise pathogenesis of it is far more understood. Hypobaic hypoxia (HH) …

Optic nerve sheath diameter increase on ascent to high altitude: correlation with acute mountain sickness

NC Kanaan, GS Lipman, BB Constance… - … of Ultrasound in …, 2015 - Wiley Online Library
Objectives Elevated optic nerve sheath diameter on sonography is known to correlate with
increased intracranial pressure and is observed in acute mountain sickness. This study …

Brain edema in diseases of different etiology

MM Adeva, G Souto, C Donapetry, M Portals… - Neurochemistry …, 2012 - Elsevier
Cerebral edema is a potentially life-threatening complication shared by diseases of different
etiology, such as diabetic ketoacidosis, acute liver failure, high altitude exposure, dialysis …