Eukaryotic DNA replication fork
PMJ Burgers, TA Kunkel - Annual review of biochemistry, 2017 - annualreviews.org
This review focuses on the biogenesis and composition of the eukaryotic DNA replication
fork, with an emphasis on the enzymes that synthesize DNA and repair discontinuities on the …
fork, with an emphasis on the enzymes that synthesize DNA and repair discontinuities on the …
Viruses of archaea: structural, functional, environmental and evolutionary genomics
M Krupovic, V Cvirkaite-Krupovic, J Iranzo… - Virus research, 2018 - Elsevier
Viruses of archaea represent one of the most enigmatic parts of the virosphere. Most of the
characterized archaeal viruses infect extremophilic hosts and display remarkable diversity of …
characterized archaeal viruses infect extremophilic hosts and display remarkable diversity of …
Asgard archaea illuminate the origin of eukaryotic cellular complexity
K Zaremba-Niedzwiedzka, EF Caceres, JH Saw… - Nature, 2017 - nature.com
The origin and cellular complexity of eukaryotes represent a major enigma in biology.
Current data support scenarios in which an archaeal host cell and an alphaproteobacterial …
Current data support scenarios in which an archaeal host cell and an alphaproteobacterial …
Archaeal clusters of orthologous genes (arCOGs): an update and application for analysis of shared features between Thermococcales, Methanococcales, and …
KS Makarova, YI Wolf, EV Koonin - Life, 2015 - mdpi.com
With the continuously accelerating genome sequencing from diverse groups of archaea and
bacteria, accurate identification of gene orthology and availability of readily expandable …
bacteria, accurate identification of gene orthology and availability of readily expandable …
DNA polymerases divide the labor of genome replication
SA Lujan, JS Williams, TA Kunkel - Trends in cell biology, 2016 - cell.com
DNA polymerases synthesize DNA in only one direction, but large genomes require RNA
priming and bidirectional replication from internal origins. We review here the physical …
priming and bidirectional replication from internal origins. We review here the physical …
Diversity and evolution of B-family DNA polymerases
B-family DNA polymerases (PolBs) represent the most common replicases. PolB enzymes
that require RNA (or DNA) primed templates for DNA synthesis are found in all domains of …
that require RNA (or DNA) primed templates for DNA synthesis are found in all domains of …
POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies
E Nicolas, EA Golemis, S Arora - Gene, 2016 - Elsevier
The evolutionarily conserved human polymerase delta (POLD1) gene encodes the large
p125 subunit which provides the essential catalytic activities of polymerase δ (Polδ) …
p125 subunit which provides the essential catalytic activities of polymerase δ (Polδ) …
On the origin of the nucleus: a hypothesis
In this hypothesis article, we explore the origin of the eukaryotic nucleus. In doing so, we first
look afresh at the nature of this defining feature of the eukaryotic cell and its core functions …
look afresh at the nature of this defining feature of the eukaryotic cell and its core functions …
Casposons: mobile genetic elements that gave rise to the CRISPR-Cas adaptation machinery
M Krupovic, P Béguin, EV Koonin - Current Opinion in Microbiology, 2017 - Elsevier
Highlights•Casposons are self-replicating mobile genetic elements found in bacteria and
archaea.•Casposase is an active casposon integrase homologous to CRISPR …
archaea.•Casposase is an active casposon integrase homologous to CRISPR …
Cultivation and Genomic Analysis of “Candidatus Nitrosocaldus islandicus,” an Obligately Thermophilic, Ammonia-Oxidizing Thaumarchaeon from a Hot Spring …
Ammonia-oxidizing archaea (AOA) within the phylum Thaumarchaeota are the only known
aerobic ammonia oxidizers in geothermal environments. Although molecular data indicate …
aerobic ammonia oxidizers in geothermal environments. Although molecular data indicate …