DAXX displays complex biological functions. Remarkably, DAXX overexpression is a
common feature in diverse cancers, which correlates with tumorigenesis, disease …

Inflammatory bowel diseases (IBDs), such as ulcerative colitis and Crohn's disease, are
chronic pathologies associated with a deregulated immune response in the intestinal …

Single-cell transcriptomics provide a systematic map of gene expression in different human
cell types. The next challenge is to systematically understand cell-type-specific gene …

Proneural genes such as Ascl1 are known to promote cell cycle exit and neuronal
differentiation when expressed in neural progenitor cells. The mechanisms by which …

Alzheimer's disease (AD) is the most common form of dementia; its pathophysiological
mechanism remains unclear. Long noncoding RNAs (lncRNAs) play key roles in AD …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common dementia among the elderly. The pathophysiology of AD is characterized by two …

The FUS gene has been linked to amyotrophic lateral sclerosis (ALS). FUS is a ubiquitous
RNA-binding protein, and the mechanisms leading to selective motoneuron loss …

Several aspects of sleep behavior such as timing, duration and quality have been
demonstrated to be heritable. To identify common variants that influence sleep traits in the …

Head and neck squamous cell carcinoma (HNSCC) is a very aggressive cancer. In
advanced stages, the patient has poor chances of receiving effective treatment, and survival …

Neurodegenerative diseases (NDs) are characterized by progressive neuronal dysfunction
and death of brain cells population. As the early manifestations of NDs are similar, their …