It has become clear that early life (including in utero exposures) is a key window of
vulnerability during which environmental exposures can alter developmental trajectories …

Understanding the determinants of human health and disease is overwhelmingly complex,
particularly for common, late-onset, chronic disorders, such as obesity and diabetes …

Depressed mood in pregnancy has been linked to low birth weight (LBW,< 2,500 g), a risk
factor for adult-onset chronic diseases in offspring. We examined maternal depressed mood …

Environmentally caused changes in chromosomes that do not alter the DNA sequence but
cause phenotypic changes by altering gene transcription are summarized as epigenetics. A …

Inter-individual variation in patterns of DNA methylation at birth can be explained by the
influence of environmental, genetic and stochastic factors. This study investigates the …

Background Epigenetic markings acquired in early life may have phenotypic consequences
later in development through their role in transcriptional regulation with relevance to the …

Background: Arsenic is an epigenetic toxicant and could influence fetal developmental
programming. Objectives: We evaluated the association between arsenic exposure and …

Exposure to chronic arsenic toxicity is associated with cancer. Although unstable genome is
a characteristic feature of cancer cells, the mechanisms leading to genomic instability in …

Aim: We investigated serum DNA methylation patterns in genomic repetitive elements, LINE-
1 and Alu, for post-traumatic stress disorder (PTSD) cases and controls who were US …

OBJECTIVE: To determine whether aberrant DNA methylation at differentially methylated
regions (DMRs) regulating insulin-like growth factor 2 (IGF2) expression in umbilical cord …