Multimorbidity, the coexistence of multiple health conditions in an individual, has emerged
as one of the greatest challenges facing health services, and this crisis is partly driven by the …

Obesity and aging are well-established risk factors for a range of diseases, including
cardiovascular diseases and type 2 diabetes. Given the escalating prevalence of obesity …

Background: Loss of functional capacity is one of the hallmarks in cardiovascular aging.
Cocoa flavanols (CF) exert favorable effects on endothelial function, blood pressure, and …

Malignant brain aging corresponds to accelerated age-related declines in brain functions
eventually derailing the self-sustaining forces that govern independent vitality. Malignant …

Heart disease is one of the principal death reasons around the world and there is a growing
requirement to discover novel healing targets that have the potential to avert or manage …

The present study was conducted to test the association between protein intake and blood
pressure, glucose levels, and blood cholesterol in a large sample of Italian older adults …

Introduction Sodium glucose co-transporter 2-inhibitors (SGLT2-I), antihyperglycemic
agents, are increasingly prescribed in chronic heart failure (CHF). Their risk for drug–drug …

Age-related alterations in cardiac function, metabolic, inflammatory and antioxidant profiles
are associated with an increased risk of cardiovascular mortality and morbidity. Here, we …

Purpose Aging contributes significantly to cardiovascular diseases and cardiac dysfunction,
leading to the upregulation of matrix metalloproteinase-9 (MMP-9) in the heart and a …

Background Ageing is a key risk factor for cardiovascular disease and is linked to several
alterations in cardiac structure and function, including left ventricular hypertrophy and …