Nowadays acute myocardial infarction (AMI) is a serious cardiovascular disease threatening
the human life and health worldwide. The most effective treatment is to quickly restore …

Simple Summary Inflammation is like the proverbial double-edged sword. Controlled short-
term inflammation could be a protective response while uncontrolled inflammation sustains …

The fetal basis of adult disease is poorly understood on a molecular level and cannot be
solely attributed to genetic mutations or a single etiology. Embryonic exposure to …

The actions of environmental toxicants and relevant mixtures in promoting the epigenetic
transgenerational inheritance of ovarian disease was investigated with the use of a …

Environmental epigenetics has an important role in regulating phenotype formation or
disease etiology. The ability of environmental factors and exposures early in life to alter …

CONTEXT: Prostate cancer (PCa) is one of the most common human malignancies and
arises through genetic and epigenetic alterations. Epigenetic modifications include DNA …

Abstract Ischemic/reperfusion (I/R) injury causes a series of serious clinical problems
associated with high morbidity and mortality in various disorders, such as acute kidney injury …

Epigenetic deregulation of gene expression has a role in the initiation and progression of
prostate cancer (PCa). The histone methyltransferase MMSET/WHSC1 (Multiple Myeloma …

Global changes in chromatin accessibility may drive cancer progression by reprogramming
transcription factor (TF) binding. In addition, histone acetylation readers such as …

Beginning with precursor lesions, aberrant DNA methylation marks the entire spectrum of
prostate cancer progression. We mapped the global DNA methylation patterns in select …