Role of aldo‐keto reductase family 1 member B1 (AKR1B1) in the cancer process and its therapeutic potential

R Khayami, SR Hashemi… - Journal of cellular and …, 2020 - Wiley Online Library
The role of aldo‐keto reductase family 1 member B1 (AKR1B1) in cancer is not totally clear
but growing evidence is suggesting to have a great impact on cancer progression. AKR1B1 …

The role of circulating free DNA and microRNA in non-invasive diagnosis of HBV-and HCV-related hepatocellular carcinoma

F Pezzuto, L Buonaguro, FM Buonaguro… - International journal of …, 2018 - mdpi.com
Hepatocellular carcinoma (HCC) is the third and the fifth leading cause of cancer related
death worldwide in men and in women, respectively. HCC generally has a poor prognosis …

Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation

D Yan, W Dong, Q He, M Yang, L Huang, J Kong… - …, 2019 - thelancet.com
Background Metastasis is a major obstacle in the treatment of bladder cancer (BC). Circular
RNAs exert various functions in the aggressive biological behaviour of cancers. In this study …

AKR1B1 represses glioma cell proliferation through p38 MAPK-mediated Bcl-2/BAX/Caspase-3 apoptotic signaling pathways

YK Huang, KC Chang, CY Li, AS Lieu… - Current issues in molecular …, 2023 - mdpi.com
This study aimed to investigate the regulatory role of Aldo-keto reductase family 1 member
B1 (AKR1B1) in glioma cell proliferation through p38 MAPK activation to control Bcl …

The tumor suppressive roles and prognostic values of STEAP family members in breast cancer

HT Wu, WJ Chen, Y Xu, JX Shen… - BioMed research …, 2020 - Wiley Online Library
Objective. To investigate the expression patterns and prognostic values of STEAP family
members in the occurrence and development of breast cancer. Materials and Methods. The …

[HTML][HTML] GSTP1 methylation in cancer: a liquid biopsy biomarker?

G Gurioli, F Martignano, S Salvi… - Clinical Chemistry and …, 2018 - degruyter.com
The coding region of GSTP1 gene is preceded by a large CpG-rich region that is frequently
affected by methylation. In many cancer types, GSTP1 is affected by hypermethylation and …

MEG3-derived miR-493-5p overcomes the oncogenic feature of IGF2-miR-483 loss of imprinting in hepatic cancer cells

L Gailhouste, LC Liew, K Yasukawa, I Hatada… - Cell Death & …, 2019 - nature.com
Numerous studies have described the critical role played by microRNAs (miRNAs) in cancer
progression and the potential of these small non-coding RNAs for diagnostic or therapeutic …

Identification of immune infiltration-related genes as prognostic indicators for hepatocellular carcinoma

K Dai, C Liu, G Guan, J Cai, L Wu - BMC cancer, 2022 - Springer
Hepatocellular carcinoma (HCC) has a high degree of malignancy and a poor prognosis.
Immune infiltration-related genes have shown good predictive value in the prognosis of …

A Six‐Gene Signature Predicts Survival of Adenocarcinoma Type of Non‐Small‐Cell Lung Cancer Patients: A Comprehensive Study Based on Integrated Analysis …

H Xie, C Xie - BioMed Research International, 2019 - Wiley Online Library
Background and Goals. To identify a multigene signature model for prognosis of non‐small‐
cell lung cancer (NSCLC) patients, we first found 2146 consensus differentially expressed …

Aberrant DOCK2, GRASP, HIF3A and PKFP Hypermethylation has Potential as a Prognostic Biomarker for Prostate Cancer

MT Bjerre, SH Strand, M Nørgaard… - International journal of …, 2019 - mdpi.com
Prostate cancer (PCa) is a clinically heterogeneous disease and currently, accurate
diagnostic and prognostic molecular biomarkers are lacking. This study aimed to identify …