Prediction of genome-wide DNA methylation in repetitive elements
DNA methylation in repetitive elements (RE) suppresses their mobility and maintains
genomic stability, and decreases in it are frequently observed in tumor and/or surrogate …
genomic stability, and decreases in it are frequently observed in tumor and/or surrogate …
Isoform‐specific localization of DNMT3A regulates DNA methylation fidelity at bivalent CpG islands
M Manzo, J Wirz, C Ambrosi, R Villaseñor… - The EMBO …, 2017 - embopress.org
DNA methylation is a prevalent epigenetic modification involved in transcriptional regulation
and essential for mammalian development. While the genome‐wide distribution of this mark …
and essential for mammalian development. While the genome‐wide distribution of this mark …
Centromere and pericentromere transcription: roles and regulation… in sickness and in health
The chromosomal loci known as centromeres (CEN) mediate the equal distribution of the
duplicated genome between both daughter cells. Specifically, centromeres recruit a protein …
duplicated genome between both daughter cells. Specifically, centromeres recruit a protein …
Epigenetic modification and therapeutic targets of diabetes mellitus
The prevalence of diabetes and its related complications are increasing significantly
globally. Collected evidence suggested that several genetic and environmental factors …
globally. Collected evidence suggested that several genetic and environmental factors …
Allele-specific H3K9me3 and DNA methylation co-marked CpG-rich regions serve as potential imprinting control regions in pre-implantation embryo
Parental DNA methylation and histone modifications undergo distinct global reprogramming
in mammalian pre-implantation embryos, but the landscape of epigenetic crosstalk and its …
in mammalian pre-implantation embryos, but the landscape of epigenetic crosstalk and its …
Histone methylation by SET domain proteins in fungi
M Freitag - Annual review of microbiology, 2017 - annualreviews.org
Histone-modifying enzymes are responsible for regulating transcription, recombination, DNA
repair, DNA replication, chromatid cohesion, and chromosome segregation. Fungi are …
repair, DNA replication, chromatid cohesion, and chromosome segregation. Fungi are …
Nutrigenomics, the microbiome, and gene-environment interactions: new directions in cardiovascular disease research, prevention, and treatment: a scientific …
JF Ferguson, H Allayee, RE Gerszten… - Circulation …, 2016 - Am Heart Assoc
Cardiometabolic diseases are the leading cause of death worldwide and are strongly linked
to both genetic and nutritional factors. The field of nutrigenomics encompasses multiple …
to both genetic and nutritional factors. The field of nutrigenomics encompasses multiple …
TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells
DNA methylation deregulation at partially methylated domains (PMDs) represents an
epigenetic signature of aging and cancer, yet the underlying molecular basis and resulting …
epigenetic signature of aging and cancer, yet the underlying molecular basis and resulting …
Glycerophosphate/acylglycerophosphate acyltransferases
A Yamashita, Y Hayashi, N Matsumoto… - Biology, 2014 - mdpi.com
Acyl-CoA: glycerol-3-phosphate acyltransferase (GPAT) and acyl-CoA: 1-acyl-glycerol-3-
phosphate acyltransferase (AGPAT) are involved in the de novo synthesis of triacylglycerol …
phosphate acyltransferase (AGPAT) are involved in the de novo synthesis of triacylglycerol …
Mechanisms of chromatin-based epigenetic inheritance
Multi-cellular organisms such as humans contain hundreds of cell types that share the same
genetic information (DNA sequences), and yet have different cellular traits and functions …
genetic information (DNA sequences), and yet have different cellular traits and functions …