Modeling the diffusion-erosion crossover dynamics in drug release

MS Gomes-Filho, FA Oliveira, MAA Barbosa - Physical Review E, 2022 - APS
A computational model is proposed to investigate drug delivery systems in which erosion
and diffusion mechanisms are participating in the drug release process. Our approach …

Multi-dimensional modeling of nanoparticles transportation from capillary bed into the tumor microenvironment

S Jafari-Matanagh, SE Razavi, MBE Bonab… - Computers in Biology …, 2023 - Elsevier
In this study, we examined the extravasation of pharmaceutical inorganic nanoparticles
(NPs) with a new approach from the leaky endothelium of tumor microvasculature (TMV) into …

Kinetics of cancer metastasis

VP Zhdanov - Biosystems, 2024 - Elsevier
The formation of metastases during cancer is now considered to be induced by migrating
metastatic stem cells (MetSCs) in preexisting niches or niches induced by MetSCs or tumor …

Spatiotemporal dynamics of tumor-CAR T-cell interaction following local administration in solid cancers

K Owens, A Rahman, I Bozic - bioRxiv, 2024 - biorxiv.org
The success of chimeric antigen receptor (CAR) T-cell therapy in treating hematologic
malignancies has generated widespread interest in translating this technology to solid …