[HTML][HTML] Involvement of the opioid peptide family in cancer progression
ML Sánchez, FD Rodríguez, R Coveñas - Biomedicines, 2023 - mdpi.com
Peptides mediate cancer progression favoring the mitogenesis, migration, and invasion of
tumor cells, promoting metastasis and anti-apoptotic mechanisms, and facilitating …
tumor cells, promoting metastasis and anti-apoptotic mechanisms, and facilitating …
[HTML][HTML] A synthetic peptide exerts nontolerance-forming antihyperalgesic and antidepressant effects in mice
Y Wu, X Song, YZ Ji, G Chen, L Zhao - Neurotherapeutics, 2024 - Elsevier
Chronic pain is a prevalent and persistent ailment that affects individuals worldwide.
Conventional medications employed in the treatment of chronic pain typically demonstrate …
Conventional medications employed in the treatment of chronic pain typically demonstrate …
Social Isolation Induces Changes in the Monoaminergic Signalling in the Rat Medial Prefrontal Cortex
V Csikós, F Dóra, T Láng, L Darai, V Szendi, A Tóth… - Cells, 2024 - mdpi.com
(1) Background: The effects of short-term social isolation during adulthood have not yet been
fully established in rats behaviourally, and not at all transcriptomically in the medial …
fully established in rats behaviourally, and not at all transcriptomically in the medial …
Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice
Introduction Dual specificity protein phosphatase 6 (DUSP6) was recently identified as a key
hub gene in a causal VGF gene network that regulates late-onset Alzheimer's disease (AD) …
hub gene in a causal VGF gene network that regulates late-onset Alzheimer's disease (AD) …
[HTML][HTML] Time-dependent ligand-receptor binding kinetics and functionality in a heterodimeric receptor model
AJ Ortiz, V Martín, D Romero, A Guillamon… - Biochemical …, 2024 - Elsevier
GPCRs heteromerize both in CNS and non-CNS regions. The cell uses receptor
heteromerization to modulate receptor functionality and to provide fine tuning of receptor …
heteromerization to modulate receptor functionality and to provide fine tuning of receptor …