[HTML][HTML] Role of vitamin D and vitamin D receptor (VDR) in oral cancer

N Fathi, E Ahmadian, S Shahi, L Roshangar… - Biomedicine & …, 2019 - Elsevier
Oral cancer is known as one of the most common cancers, with a poor prognosis, related to
delayed clinical diagnosis, either due to the lack of particular biomarkers related to the …

Endogenously produced nonclassical vitamin D hydroxy-metabolites act as “biased” agonists on VDR and inverse agonists on RORα and RORγ

AT Slominski, TK Kim, JV Hobrath, ASW Oak… - The Journal of steroid …, 2017 - Elsevier
The classical pathway of vitamin D activation follows the sequence D3→ 25 (OH) D3→ 1, 25
(OH) 2 D3 with the final product acting on the receptor for vitamin D (VDR). An alternative …

[HTML][HTML] Effect of vitamin D supplementation on risk of breast cancer: a systematic review and meta-analysis of randomized controlled trials

Z Li, L Wu, J Zhang, X Huang, L Thabane, G Li - Frontiers in nutrition, 2021 - frontiersin.org
Objective: Laboratory findings indicated that vitamin D might have a potent protective effect
on breast cancer, but epidemiology studies reported conflicting results. The aim of the study …

Vitamin D metabolism in dogs and cats and its relation to diseases not associated with bone metabolism

RVA Zafalon, LW Risolia, V Pedrinelli… - Journal of animal …, 2020 - Wiley Online Library
Due to the presence of receptors in the cells of numerous body tissues, vitamin D is
associated with several physiological functions that go beyond calcium and phosphorus …

[HTML][HTML] Biological evaluation of combinations of tyrosine kinase inhibitors with Inecalcitol as novel treatments for human chronic myeloid leukemia

L Al-Ali, RJ Al-Ani, MM Saleh, AM Hammad… - Saudi Pharmaceutical …, 2024 - Elsevier
Background The use of tyrosine kinase inhibitors (TKIs) as a treatment for chronic myeloid
leukemia (CML) has improved the natural history of the disease and increased the duration …

Therapeutic effects of vitamin D and cancer: An overview

JE Varghese, B Balasubramanian… - Food …, 2021 - Wiley Online Library
Since vitamin D's discovery, strenuous efforts to investigate its physiological exploit and
deficiency on human health were done. Our body synthesizes fat‐soluble vitamin D when …

The role of geographical ecological studies in identifying diseases linked to UVB exposure and/or vitamin D

WB Grant - Dermato-endocrinology, 2016 - Taylor & Francis
Using a variety of approaches, researchers have studied the health effects of solar ultraviolet
(UV) radiation exposure and vitamin D. This review compares the contributions from …

[HTML][HTML] Exploring the role of metabolites in cancer and the associated nerve crosstalk

I Gu, E Gregory, C Atwood, SO Lee, YH Song - Nutrients, 2022 - mdpi.com
Since Otto Warburg's first report on the increased uptake of glucose and lactate release by
cancer cells, dysregulated metabolism has been acknowledged as a hallmark of cancer that …

Vitamin D derivatives enhance cytotoxic effects of H2O2 or cisplatin on human keratinocytes

A Piotrowska, J Wierzbicka, T Ślebioda, M Woźniak… - Steroids, 2016 - Elsevier
Although the skin production of vitamin D is initiated by ultraviolet radiation type B (UVB), the
role vitamin D plays in antioxidative or pro-oxidative responses remains to be elucidated …

[HTML][HTML] Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer

A Anisiewicz, A Pawlik… - International …, 2018 - spandidos-publications.com
Low vitamin D status is considered as a risk factor for breast cancer and has prognostic
significance. Furthermore, vitamin D deficiency increases after adjuvant cancer therapy …