[HTML][HTML] Sex differences in the blood–brain barrier: implications for mental health

L Dion-Albert, LB Binder, B Daigle, A Hong-Minh… - Frontiers in …, 2022 - Elsevier
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

Sex differences in cerebral aneurysms and subarachnoid hemorrhage

AM Fuentes, L Stone McGuire, S Amin-Hanjani - Stroke, 2022 - Am Heart Assoc
Sex differences in cerebral aneurysm occurrence and characteristics have been well
described. Although sex differences in outcomes following ischemic stroke have been …

Artificial intelligence velocimetry reveals in vivo flow rates, pressure gradients, and shear stresses in murine perivascular flows

KAS Boster, S Cai… - Proceedings of the …, 2023 - National Acad Sciences
Quantifying the flow of cerebrospinal fluid (CSF) is crucial for understanding brain waste
clearance and nutrient delivery, as well as edema in pathological conditions such as stroke …

Vascular smooth muscle cells in intracranial aneurysms

Z Wang, J Ma, H Yue, Z Zhang, F Fang, G Wang… - Microvascular …, 2023 - Elsevier
Intracranial aneurysm (IA) is a severe cerebrovascular disease characterized by abnormal
bulging of cerebral vessels that may rupture and cause a stroke. The expansion of the …

Comprehensive analysis of mitochondrial dysfunction and necroptosis in intracranial aneurysms from the perspective of predictive, preventative, and personalized …

B Chen, K Xie, J Zhang, L Yang, H Zhou, L Zhang… - Apoptosis, 2023 - Springer
Mitochondrial dysfunction and necroptosis are closely associated, and play vital roles in the
medical strategy of multiple cardiovascular diseases. However, their implications in …

Single-cell RNA sequencing reveals the pathogenic relevance of intracranial atherosclerosis in blood blister-like aneurysms

D Wen, X Wang, R Chen, H Li, J Zheng, W Fu… - Frontiers in …, 2022 - frontiersin.org
Background Intracranial non-branching site blood blister-like aneurysms (BBA) are
extremely rare and vicious. Their etiology remains elusive, and no molecular study has been …

Objective quantification of contrast enhancement of unruptured intracranial aneurysms: a high-resolution vessel wall imaging validation study

JA Roa, M Zanaty, C Osorno-Cruz, D Ishii… - Journal of …, 2020 - thejns.org
OBJECTIVE High-resolution vessel wall imaging (HR-VWI) has emerged as a valuable tool
in assessing unruptured intracranial aneurysms (UIAs). There is no standardized method to …

Why are women predisposed to intracranial aneurysm?

M Fréneau, C Baron-Menguy, AC Vion… - Frontiers in …, 2022 - frontiersin.org
Intracranial aneurysm (IA) is a frequent and generally asymptomatic cerebrovascular
abnormality characterized as a localized dilation and wall thinning of intracranial arteries …

Neuroprotective strategies in aneurysmal subarachnoid hemorrhage (aSAH)

J Weiland, A Beez, T Westermaier, E Kunze… - International Journal of …, 2021 - mdpi.com
Aneurysmal subarachnoid hemorrhage (aSAH) remains a disease with high mortality and
morbidity. Since treating vasospasm has not inevitably led to an improvement in outcome …

The Potential of NLRP3 inflammasome as a therapeutic target in neurological diseases

W He, Z Hu, Y Zhong, C Wu, J Li - Molecular Neurobiology, 2023 - Springer
Abstract NLRP3 (NLRP3: NOD-, LRR-, and pyrin domain-containing protein 3)
inflammasome is the best-described inflammasome that plays a crucial role in the innate …